GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
olfactory receptor family 5 subfamily R member 1 (gene/pseudogene)ENSG00000279961OR5R1chr11:56417258-56418232:-55.5
olfactory receptor family 1 subfamily S member 1 (gene/pseudogene)ENSG00000280204OR1S1chr11:58214745-58215723:+55.5
GRB2 associated binding protein 2ENSG00000033327GAB2chr11:78215297-78418348:-55.5
dynein cytoplasmic 2 heavy chain 1ENSG00000187240DYNC2H1chr11:103109431-103479863:+57.5
olfactory receptor family 8 subfamily G member 2 pseudogeneENSG00000181214OR8G2Pchr11:124224732-124225639:+55.5
olfactory receptor family 4 subfamily K member 3 (gene/pseudogene)ENSG00000176290OR4K3chr14:19868242-19869143:-55.5
calcium and integrin binding 1ENSG00000185043CIB1chr15:90229975-90234047:-57
serine protease 41ENSG00000215148PRSS41chr16:2798485-2805132:+55
vomeronasal 1 receptor 3 (gene/pseudogene)ENSG00000180663VN1R3chr16:31807926-31808844:-55.5
olfactory receptor family 1 subfamily P member 1 (gene/pseudogene)ENSG00000262085OR1P1chr17:3153889-3154882:-55.5
olfactory receptor family 1 subfamily D member 4 (gene/pseudogene)ENSG00000255095OR1D4chr17:3240676-3241614:+55.5
olfactory receptor family 3 subfamily A member 4 pseudogeneENSG00000180068OR3A4Pchr17:3310312-3311189:+55.5
src kinase associated phosphoprotein 1ENSG00000141293SKAP1chr17:48133440-48430275:-67
sphingosine kinase 1ENSG00000176170SPHK1chr17:76376584-76387860:+56
YES proto-oncogene 1, Src family tyrosine kinaseENSG00000176105YES1chr18:721588-812546:-610
interferon lambda 1ENSG00000182393IFNL1chr19:39296325-39298673:+55.5
protein tyrosine phosphatase non-receptor type 4ENSG00000088179PTPN4chr2:119759631-119983818:+55
carboxypeptidase OENSG00000144410CPOchr2:206939554-206969474:+55
dual specificity phosphatase 15ENSG00000149599DUSP15chr20:31847637-31870747:-55
SRC proto-oncogene, non-receptor tyrosine kinaseENSG00000197122SRCchr20:37344685-37406050:+69

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