GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
HCK proto-oncogene, Src family tyrosine kinase | ENSG00000101336 | HCK | chr20:32052188-32101856:+ | 6 | 8.5 |
contactin 4 | ENSG00000144619 | CNTN4 | chr3:2098813-3057956:+ | 6 | 6.5 |
lipoprotein lipase | ENSG00000175445 | LPL | chr8:19901717-19967258:+ | 5 | 6 |
glycosylphosphatidylinositol anchored molecule like | ENSG00000104499 | GML | chr8:142834247-142916506:+ | 5 | 5 |
cyclin dependent kinase 16 | ENSG00000102225 | CDK16 | chrX:47217860-47229997:+ | 5 | 6.5 |
olfactory receptor family 10 subfamily X member 1 (gene/pseudogene) | ENSG00000279111 | OR10X1 | chr1:158578919-158579899:- | 5 | 5.5 |
olfactory receptor family 10 subfamily J member 4 (gene/pseudogene) | ENSG00000249730 | OR10J4 | chr1:159432204-159433138:+ | 5 | 5.5 |
olfactory receptor family 10 subfamily J member 6 pseudogene | ENSG00000158731 | OR10J6P | chr1:159598298-159599227:+ | 6 | 6.5 |
olfactory receptor family 2 subfamily L member 8 (gene/pseudogene) | ENSG00000279263 | OR2L8 | chr1:247948858-247949796:+ | 5 | 5.5 |
shadow of prion protein | ENSG00000203772 | SPRN | chr10:133420666-133424572:- | 5 | 5 |
olfactory receptor family 51 subfamily F member 1 (gene/pseudogene) | ENSG00000280021 | OR51F1 | chr11:4768979-4769938:- | 6 | 6.5 |
olfactory receptor family 52 subfamily R member 1 (gene/pseudogene) | ENSG00000279270 | OR52R1 | chr11:4803433-4804380:- | 6 | 6.5 |
olfactory receptor family 52 subfamily E member 1 (gene/pseudogene) | ENSG00000273085 | OR52E1 | chr11:5069572-5070497:+ | 6 | 6.5 |
olfactory receptor family 56 subfamily B member 2 pseudogene | ENSG00000181017 | OR56B2P | chr11:5765096-5766049:+ | 6 | 6.5 |
amyloid beta precursor protein binding family B member 1 | ENSG00000166313 | APBB1 | chr11:6395124-6419414:- | 5 | 6 |
olfactory receptor family 4 subfamily X member 2 (gene/pseudogene) | ENSG00000172208 | OR4X2 | chr11:48245056-48246080:+ | 5 | 5.5 |
olfactory receptor family 4 subfamily C member 45 (gene/pseudogene) | ENSG00000260811 | OR4C45 | chr11:50032874-50033794:+ | 5 | 5.5 |
olfactory receptor family 4 subfamily A member 8 (gene/pseudogene) | ENSG00000225997 | OR4A8 | chr11:54682877-54683821:+ | 5 | 5.5 |
olfactory receptor family 4 subfamily C member 16 (gene/pseudogene) | ENSG00000279514 | OR4C16 | chr11:55572128-55573060:+ | 5 | 5.5 |
olfactory receptor family 5 subfamily D member 13 (gene/pseudogene) | ENSG00000279761 | OR5D13 | chr11:55773438-55774382:+ | 5 | 5.5 |
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