GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
progestin and adipoQ receptor family member 9ENSG00000188582PAQR9chr3:142949164-142963682:-56.5
CLPTM1 likeENSG00000049656CLPTM1Lchr5:1317744-1345099:-510.5
lymphotoxin betaENSG00000227507LTBchr6:31580525-31582522:-57.5
potassium two pore domain channel subfamily K member 17ENSG00000124780KCNK17chr6:39299001-39314553:-68.5
vanin 3ENSG00000093134VNN3chr6:132722787-132734765:-57
polycystin 1 like 1, transient receptor potential channel interactingENSG00000158683PKD1L1chr7:47774652-47948491:-57.5
proline rich transmembrane protein 4ENSG00000224940PRRT4chr7:128350325-128361685:-56.5
hyaluronan synthase 2ENSG00000170961HAS2chr8:121612116-121641390:-67.5
lymphocyte antigen 6 family member HENSG00000176956LY6Hchr8:143157914-143160711:-56.5
potassium voltage-gated channel subfamily D member 1ENSG00000102057KCND1chrX:48961378-48971569:-67.5
LY6/PLAUR domain containing 8ENSG00000259823LYPD8chr1:248718649-248755739:-55.5
inositol 1,4,5-trisphosphate receptor interacting proteinENSG00000148841ITPRIPchr10:104309698-104338404:-56.5
placenta expressed transcript 1ENSG00000188771PLET1chr11:112248479-112260860:-66.5
RAB5C, member RAS oncogene familyENSG00000108774RAB5Cchr17:42124976-42155044:-512.5
ectonucleotide pyrophosphatase/phosphodiesterase 7ENSG00000182156ENPP7chr17:79730919-79742222:+55
ephrin A2ENSG00000099617EFNA2chr19:1286154-1300237:+66.5
C3 and PZP like alpha-2-macroglobulin domain containing 8ENSG00000160111CPAMD8chr19:16892947-17026815:-55.5
GNAS complex locusENSG00000087460GNASchr20:58839718-58911192:+614
contactin 6ENSG00000134115CNTN6chr3:1092576-1404217:+66.5
semaphorin 3DENSG00000153993SEMA3Dchr7:84995553-85186855:-67.5

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