GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
progestin and adipoQ receptor family member 9 | ENSG00000188582 | PAQR9 | chr3:142949164-142963682:- | 5 | 6.5 |
CLPTM1 like | ENSG00000049656 | CLPTM1L | chr5:1317744-1345099:- | 5 | 10.5 |
lymphotoxin beta | ENSG00000227507 | LTB | chr6:31580525-31582522:- | 5 | 7.5 |
potassium two pore domain channel subfamily K member 17 | ENSG00000124780 | KCNK17 | chr6:39299001-39314553:- | 6 | 8.5 |
vanin 3 | ENSG00000093134 | VNN3 | chr6:132722787-132734765:- | 5 | 7 |
polycystin 1 like 1, transient receptor potential channel interacting | ENSG00000158683 | PKD1L1 | chr7:47774652-47948491:- | 5 | 7.5 |
proline rich transmembrane protein 4 | ENSG00000224940 | PRRT4 | chr7:128350325-128361685:- | 5 | 6.5 |
hyaluronan synthase 2 | ENSG00000170961 | HAS2 | chr8:121612116-121641390:- | 6 | 7.5 |
lymphocyte antigen 6 family member H | ENSG00000176956 | LY6H | chr8:143157914-143160711:- | 5 | 6.5 |
potassium voltage-gated channel subfamily D member 1 | ENSG00000102057 | KCND1 | chrX:48961378-48971569:- | 6 | 7.5 |
LY6/PLAUR domain containing 8 | ENSG00000259823 | LYPD8 | chr1:248718649-248755739:- | 5 | 5.5 |
inositol 1,4,5-trisphosphate receptor interacting protein | ENSG00000148841 | ITPRIP | chr10:104309698-104338404:- | 5 | 6.5 |
placenta expressed transcript 1 | ENSG00000188771 | PLET1 | chr11:112248479-112260860:- | 6 | 6.5 |
RAB5C, member RAS oncogene family | ENSG00000108774 | RAB5C | chr17:42124976-42155044:- | 5 | 12.5 |
ectonucleotide pyrophosphatase/phosphodiesterase 7 | ENSG00000182156 | ENPP7 | chr17:79730919-79742222:+ | 5 | 5 |
ephrin A2 | ENSG00000099617 | EFNA2 | chr19:1286154-1300237:+ | 6 | 6.5 |
C3 and PZP like alpha-2-macroglobulin domain containing 8 | ENSG00000160111 | CPAMD8 | chr19:16892947-17026815:- | 5 | 5.5 |
GNAS complex locus | ENSG00000087460 | GNAS | chr20:58839718-58911192:+ | 6 | 14 |
contactin 6 | ENSG00000134115 | CNTN6 | chr3:1092576-1404217:+ | 6 | 6.5 |
semaphorin 3D | ENSG00000153993 | SEMA3D | chr7:84995553-85186855:- | 6 | 7.5 |
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