GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
ethanolamine kinase 1ENSG00000139163ETNK1chr12:22625075-22690665:+57.5
solute carrier family 38 member 7ENSG00000103042SLC38A7chr16:58665109-58685104:-57.5
phosphatidylinositol glycan anchor biosynthesis class WENSG00000277161PIGWchr17:36535020-36539310:+67.5
monocyte to macrophage differentiation associatedENSG00000108960MMDchr17:55392613-55421992:-56.5
potassium inwardly rectifying channel subfamily J member 2ENSG00000123700KCNJ2chr17:70168673-70180048:+56.5
otopetrin 3ENSG00000182938OTOP3chr17:74935719-74949992:+56.5
potassium voltage-gated channel modifier subfamily G member 2ENSG00000178342KCNG2chr18:79863668-79900184:+67.5
transmembrane protein 259ENSG00000182087TMEM259chr19:1009648-1021179:-610.5
solute carrier family 27 member 1ENSG00000130304SLC27A1chr19:17468769-17506168:+69
potassium inwardly rectifying channel subfamily J member 14ENSG00000182324KCNJ14chr19:48455509-48466980:+56.5
potassium voltage-gated channel subfamily A member 7ENSG00000104848KCNA7chr19:49067418-49072941:-67.5
solute carrier family 20 member 1ENSG00000144136SLC20A1chr2:112645857-112663827:+69.5
LY6/PLAUR domain containing 1ENSG00000150551LYPD1chr2:132644853-132671579:-56
acid sensing ion channel subunit family member 4ENSG00000072182ASIC4chr2:219514170-219538772:+56
transmembrane channel like 2ENSG00000149488TMC2chr20:2536607-2641784:+56.5
intersectin 1ENSG00000205726ITSN1chr21:33642400-33899861:+57
potassium inwardly rectifying channel subfamily J member 6ENSG00000157542KCNJ6chr21:37607376-37916446:-56.5
immunoglobulin superfamily member 5ENSG00000183067IGSF5chr21:39745407-39802096:+55.5
ATP binding cassette subfamily G member 1ENSG00000160179ABCG1chr21:42199689-42297244:+56.5
transmembrane protein 121BENSG00000183307CECR6chr22:17116299-17121367:-56.5

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