GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
ethanolamine kinase 1 | ENSG00000139163 | ETNK1 | chr12:22625075-22690665:+ | 5 | 7.5 |
solute carrier family 38 member 7 | ENSG00000103042 | SLC38A7 | chr16:58665109-58685104:- | 5 | 7.5 |
phosphatidylinositol glycan anchor biosynthesis class W | ENSG00000277161 | PIGW | chr17:36535020-36539310:+ | 6 | 7.5 |
monocyte to macrophage differentiation associated | ENSG00000108960 | MMD | chr17:55392613-55421992:- | 5 | 6.5 |
potassium inwardly rectifying channel subfamily J member 2 | ENSG00000123700 | KCNJ2 | chr17:70168673-70180048:+ | 5 | 6.5 |
otopetrin 3 | ENSG00000182938 | OTOP3 | chr17:74935719-74949992:+ | 5 | 6.5 |
potassium voltage-gated channel modifier subfamily G member 2 | ENSG00000178342 | KCNG2 | chr18:79863668-79900184:+ | 6 | 7.5 |
transmembrane protein 259 | ENSG00000182087 | TMEM259 | chr19:1009648-1021179:- | 6 | 10.5 |
solute carrier family 27 member 1 | ENSG00000130304 | SLC27A1 | chr19:17468769-17506168:+ | 6 | 9 |
potassium inwardly rectifying channel subfamily J member 14 | ENSG00000182324 | KCNJ14 | chr19:48455509-48466980:+ | 5 | 6.5 |
potassium voltage-gated channel subfamily A member 7 | ENSG00000104848 | KCNA7 | chr19:49067418-49072941:- | 6 | 7.5 |
solute carrier family 20 member 1 | ENSG00000144136 | SLC20A1 | chr2:112645857-112663827:+ | 6 | 9.5 |
LY6/PLAUR domain containing 1 | ENSG00000150551 | LYPD1 | chr2:132644853-132671579:- | 5 | 6 |
acid sensing ion channel subunit family member 4 | ENSG00000072182 | ASIC4 | chr2:219514170-219538772:+ | 5 | 6 |
transmembrane channel like 2 | ENSG00000149488 | TMC2 | chr20:2536607-2641784:+ | 5 | 6.5 |
intersectin 1 | ENSG00000205726 | ITSN1 | chr21:33642400-33899861:+ | 5 | 7 |
potassium inwardly rectifying channel subfamily J member 6 | ENSG00000157542 | KCNJ6 | chr21:37607376-37916446:- | 5 | 6.5 |
immunoglobulin superfamily member 5 | ENSG00000183067 | IGSF5 | chr21:39745407-39802096:+ | 5 | 5.5 |
ATP binding cassette subfamily G member 1 | ENSG00000160179 | ABCG1 | chr21:42199689-42297244:+ | 5 | 6.5 |
transmembrane protein 121B | ENSG00000183307 | CECR6 | chr22:17116299-17121367:- | 5 | 6.5 |
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