GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
LHFPL tetraspan subfamily member 5 | ENSG00000197753 | LHFPL5 | chr6:35805293-35833874:+ | 5 | 6.5 |
potassium two pore domain channel subfamily K member 5 | ENSG00000164626 | KCNK5 | chr6:39188973-39229450:- | 6 | 7.5 |
Yip1 domain family member 3 | ENSG00000137207 | YIPF3 | chr6:43511827-43516990:- | 5 | 9.5 |
progestin and adipoQ receptor family member 8 | ENSG00000170915 | PAQR8 | chr6:52361421-52407777:+ | 6 | 7.5 |
solute carrier family 22 member 2 | ENSG00000112499 | SLC22A2 | chr6:160171061-160277638:- | 5 | 6.5 |
solute carrier family 22 member 3 | ENSG00000146477 | SLC22A3 | chr6:160348268-160452581:+ | 5 | 7.5 |
lemur tyrosine kinase 2 | ENSG00000164715 | LMTK2 | chr7:98106885-98209633:+ | 6 | 8.5 |
solute carrier family 13 member 4 | ENSG00000164707 | SLC13A4 | chr7:135681237-135729258:- | 5 | 6.5 |
TNF receptor superfamily member 10b | ENSG00000120889 | TNFRSF10B | chr8:23020133-23069179:- | 6 | 12.5 |
phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | ENSG00000076641 | PAG1 | chr8:80967810-81112068:- | 5 | 7.5 |
G protein-coupled receptor 107 | ENSG00000148358 | GPR107 | chr9:130053426-130140169:+ | 5 | 8.5 |
solute carrier family 34 member 3 | ENSG00000198569 | SLC34A3 | chr9:137230757-137236554:+ | 6 | 7.5 |
calcium voltage-gated channel subunit alpha1 B | ENSG00000148408 | CACNA1B | chr9:137877789-138124624:+ | 5 | 8.5 |
tetraspanin 7 | ENSG00000156298 | TSPAN7 | chrX:38561370-38688920:+ | 6 | 7.5 |
potassium voltage-gated channel subfamily C member 4 | ENSG00000116396 | KCNC4 | chr1:110211343-110283100:+ | 6 | 7.5 |
potassium voltage-gated channel subfamily A member 10 | ENSG00000143105 | KCNA10 | chr1:110517251-110518838:- | 6 | 7.5 |
cyclin and CBS domain divalent metal cation transport mediator 1 | ENSG00000119946 | CNNM1 | chr10:99329099-99394330:+ | 5 | 6 |
tectorin beta | ENSG00000119913 | TECTB | chr10:112283735-112305035:+ | 5 | 6 |
ADP-ribosyltransferase 1 | ENSG00000129744 | ART1 | chr11:3645128-3664416:+ | 5 | 6 |
microtubule affinity regulating kinase 2 | ENSG00000072518 | MARK2 | chr11:63838928-63911019:+ | 5 | 8 |
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