GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
endothelin converting enzyme like 1ENSG00000171551ECEL1chr2:232479827-232487828:-56.5
solute carrier family 4 member 11ENSG00000088836SLC4A11chr20:3227417-3239190:-57.5
purinergic receptor P2X 6ENSG00000099957P2RX6chr22:21009808-21028830:+67.5
solute carrier family 5 member 4ENSG00000100191SLC5A4chr22:32218476-32255341:-67.5
calcium voltage-gated channel subunit alpha1 IENSG00000100346CACNA1Ichr22:39570753-39689737:+67.5
TNF receptor superfamily member 13CENSG00000159958TNFRSF13Cchr22:41922023-41926818:-58.5
LHFPL tetraspan subfamily member 4ENSG00000156959LHFPL4chr3:9498361-9553802:-56.5
solute carrier family 35 member G2ENSG00000168917SLC35G2chr3:136818647-136855892:+56.5
solute carrier family 2 member 2ENSG00000163581SLC2A2chr3:170996348-171026750:-56.5
chloride voltage-gated channel 2ENSG00000114859CLCN2chr3:184346185-184361651:-69.5
ATPase 13A3ENSG00000133657ATP13A3chr3:194402672-194498364:-510.5
solute carrier family 10 member 4ENSG00000145248SLC10A4chr4:48483343-48489196:+56.5
solute carrier family 9 member B2ENSG00000164038SLC9B2chr4:103019868-103085829:-56.5
solute carrier family 6 member 18ENSG00000164363SLC6A18chr5:1225355-1246189:+67.5
ANKH inorganic pyrophosphate transport regulatorENSG00000154122ANKHchr5:14704804-14871778:-58.5
repulsive guidance molecule BMP co-receptor bENSG00000174136RGMBchr5:98768650-98798643:+611
solute carrier family 6 member 7ENSG00000011083SLC6A7chr5:150189957-150222788:+67.5
potassium calcium-activated channel subfamily M regulatory beta subunit 1ENSG00000145936KCNMB1chr5:170374671-170389677:-67.5
tumor necrosis factorENSG00000232810TNFchr6:31575567-31578336:+56.5
lymphocyte antigen 6 family member G6CENSG00000204421LY6G6Cchr6:31718648-31721845:-67.5

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