GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
endothelin converting enzyme like 1 | ENSG00000171551 | ECEL1 | chr2:232479827-232487828:- | 5 | 6.5 |
solute carrier family 4 member 11 | ENSG00000088836 | SLC4A11 | chr20:3227417-3239190:- | 5 | 7.5 |
purinergic receptor P2X 6 | ENSG00000099957 | P2RX6 | chr22:21009808-21028830:+ | 6 | 7.5 |
solute carrier family 5 member 4 | ENSG00000100191 | SLC5A4 | chr22:32218476-32255341:- | 6 | 7.5 |
calcium voltage-gated channel subunit alpha1 I | ENSG00000100346 | CACNA1I | chr22:39570753-39689737:+ | 6 | 7.5 |
TNF receptor superfamily member 13C | ENSG00000159958 | TNFRSF13C | chr22:41922023-41926818:- | 5 | 8.5 |
LHFPL tetraspan subfamily member 4 | ENSG00000156959 | LHFPL4 | chr3:9498361-9553802:- | 5 | 6.5 |
solute carrier family 35 member G2 | ENSG00000168917 | SLC35G2 | chr3:136818647-136855892:+ | 5 | 6.5 |
solute carrier family 2 member 2 | ENSG00000163581 | SLC2A2 | chr3:170996348-171026750:- | 5 | 6.5 |
chloride voltage-gated channel 2 | ENSG00000114859 | CLCN2 | chr3:184346185-184361651:- | 6 | 9.5 |
ATPase 13A3 | ENSG00000133657 | ATP13A3 | chr3:194402672-194498364:- | 5 | 10.5 |
solute carrier family 10 member 4 | ENSG00000145248 | SLC10A4 | chr4:48483343-48489196:+ | 5 | 6.5 |
solute carrier family 9 member B2 | ENSG00000164038 | SLC9B2 | chr4:103019868-103085829:- | 5 | 6.5 |
solute carrier family 6 member 18 | ENSG00000164363 | SLC6A18 | chr5:1225355-1246189:+ | 6 | 7.5 |
ANKH inorganic pyrophosphate transport regulator | ENSG00000154122 | ANKH | chr5:14704804-14871778:- | 5 | 8.5 |
repulsive guidance molecule BMP co-receptor b | ENSG00000174136 | RGMB | chr5:98768650-98798643:+ | 6 | 11 |
solute carrier family 6 member 7 | ENSG00000011083 | SLC6A7 | chr5:150189957-150222788:+ | 6 | 7.5 |
potassium calcium-activated channel subfamily M regulatory beta subunit 1 | ENSG00000145936 | KCNMB1 | chr5:170374671-170389677:- | 6 | 7.5 |
tumor necrosis factor | ENSG00000232810 | TNF | chr6:31575567-31578336:+ | 5 | 6.5 |
lymphocyte antigen 6 family member G6C | ENSG00000204421 | LY6G6C | chr6:31718648-31721845:- | 6 | 7.5 |
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