GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
P2Y receptor family member 8ENSG00000182162P2RY8chrX:1462572-1537107:-1216.5
TNF receptor superfamily member 14ENSG00000157873TNFRSF14chr1:2555639-2565382:+1215.5
EPH receptor B2ENSG00000133216EPHB2chr1:22710839-22921500:+1218.5
leptin receptorENSG00000116678LEPRchr1:65420652-65641559:+1214.5
transforming growth factor beta receptor 3ENSG00000069702TGFBR3chr1:91680343-91906335:-1113.5
colony stimulating factor 1ENSG00000184371CSF1chr1:109910242-109930992:+1115.5
platelet endothelial aggregation receptor 1ENSG00000187800PEAR1chr1:156893698-156916434:+1114.5
CD1c moleculeENSG00000158481CD1Cchr1:158289786-158293630:+1214.5
CD1b moleculeENSG00000158485CD1Bchr1:158327951-158331531:-1213.5
cell adhesion molecule 3ENSG00000162706CADM3chr1:159171609-159203313:+1112.5
Fc fragment of IgG receptor IIaENSG00000143226FCGR2Achr1:161505430-161524013:+1114.5
discoidin domain receptor tyrosine kinase 2ENSG00000162733DDR2chr1:162631373-162787400:+1217.5
ATPase Na+/K+ transporting subunit beta 1ENSG00000143153ATP1B1chr1:169105697-169132722:+1219.5
complement C3d receptor 2ENSG00000117322CR2chr1:207454230-207489895:+1114.5
CD34 moleculeENSG00000174059CD34chr1:207880972-207911402:-1114.5
interleukin 2 receptor subunit alphaENSG00000134460IL2RAchr10:6010689-6062325:-1113.5
solute carrier family 29 member 2ENSG00000174669SLC29A2chr11:66362521-66372214:-1216.5
endothelial cell adhesion moleculeENSG00000149564ESAMchr11:124752583-124762290:-1114.5
amyloid beta precursor like protein 2ENSG00000084234APLP2chr11:130069837-130144811:+1117.5
CD27 moleculeENSG00000139193CD27chr12:6444867-6451718:+1215.5

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