GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
solute carrier family 12 member 1ENSG00000074803SLC12A1chr15:48191664-48304078:+67.5
aquaporin 9ENSG00000103569AQP9chr15:58138169-58185911:+56.5
aquaporin 8ENSG00000103375AQP8chr16:25215731-25228940:+56.5
proline rich transmembrane protein 2ENSG00000167371PRRT2chr16:29811382-29815892:+56.5
CDP-diacylglycerol--inositol 3-phosphatidyltransferaseENSG00000103502CDIPTchr16:29858357-29863736:-59.5
solute carrier family 5 member 2ENSG00000140675SLC5A2chr16:31483002-31490860:+67.5
solute carrier family 43 member 2ENSG00000167703SLC43A2chr17:1569267-1628886:-57.5
solute carrier family 5 member 10ENSG00000154025SLC5A10chr17:18950345-19022595:+67.5
calcium voltage-gated channel auxiliary subunit gamma 5ENSG00000075429CACNG5chr17:66835117-66885486:+56.5
otopetrin 2ENSG00000183034OTOP2chr17:74924275-74933912:+56.5
calcium activated nucleotidase 1ENSG00000171302CANT1chr17:78991717-79009867:-58.5
CACN subunit beta associated regulatory proteinENSG00000099625C19orf26chr19:1228287-1238027:-57.5
solute carrier family 5 member 5ENSG00000105641SLC5A5chr19:17871973-17895174:+56.5
ATPase 13A1ENSG00000105726ATP13A1chr19:19645198-19663693:-511.5
solute carrier family 7 member 10ENSG00000130876SLC7A10chr19:33208664-33225850:-57.5
uroplakin 1AENSG00000105668UPK1Achr19:35666516-35678483:+67.5
testis expressed 101ENSG00000131126TEX101chr19:43401496-43418597:+56
LY6/PLAUR domain containing 5ENSG00000159871LYPD5chr19:43795929-43827206:-67
solute carrier family 17 member 7ENSG00000104888SLC17A7chr19:49429401-49442360:-67.5
potassium voltage-gated channel modifier subfamily S member 3ENSG00000170745KCNS3chr2:17877847-18361616:+67.5

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