GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
leucine rich repeat containing 8 VRAC subunit DENSG00000171492LRRC8Dchr1:89821014-89936611:+59.5
presenilin 2ENSG00000143801PSEN2chr1:226870184-226896105:+68.5
solute carrier family 16 member 9ENSG00000165449SLC16A9chr10:59650761-59736002:-56.5
solute carrier family 18 member A2ENSG00000165646SLC18A2chr10:117241093-117279430:+67.5
interferon induced transmembrane protein 1ENSG00000185885IFITM1chr11:313506-315272:+610.5
anoctamin 3ENSG00000134343ANO3chr11:26309599-26663288:+56.5
solute carrier family 43 member 3ENSG00000134802SLC43A3chr11:57406954-57427580:-611.5
tectorin alphaENSG00000109927TECTAchr11:121101173-121191493:+56.5
potassium inwardly rectifying channel subfamily J member 1ENSG00000151704KCNJ1chr11:128836315-128867373:-56.5
solute carrier family 6 member 12ENSG00000111181SLC6A12chr12:190077-214570:-67.5
leucine rich repeats and immunoglobulin like domains 3ENSG00000139263LRIG3chr12:58872149-58920522:-57.5
anoctamin 4ENSG00000151572ANO4chr12:100717526-101128641:+56.5
signal peptide peptidase like 3ENSG00000157837SPPL3chr12:120762510-120904371:-67.5
ATPase phospholipid transporting 8A2ENSG00000132932ATP8A2chr13:25372071-26025851:+68.5
ATPase copper transporting betaENSG00000123191ATP7Bchr13:51932673-52011494:-67.5
adenylate cyclase 4ENSG00000129467ADCY4chr14:24318349-24335093:-67.5
MAM domain containing glycosylphosphatidylinositol anchor 2ENSG00000139915MDGA2chr14:46839629-47674954:-56.5
solute carrier family 10 member 1ENSG00000100652SLC10A1chr14:69775417-69797289:-56.5
serine peptidase inhibitor, Kunitz type 1ENSG00000166145SPINT1chr15:40844018-40858207:+510.5
solute carrier family 28 member 2ENSG00000137860SLC28A2chr15:45252230-45277845:+67.5

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