GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
transmembrane protein 184AENSG00000164855TMEM184Achr7:1542235-1560821:-57
calneuron 1ENSG00000183166CALN1chr7:71779491-72447151:-56.5
leucine rich repeat containing 4ENSG00000128594LRRC4chr7:128027071-128032107:-56.5
EPH receptor B6ENSG00000106123EPHB6chr7:142855061-142871094:+68.5
ADAM metallopeptidase domain 2ENSG00000104755ADAM2chr8:39743735-39838289:-56.5
sodium/potassium transporting ATPase interacting 3ENSG00000185942NKAIN3chr8:62248591-62999652:+56.5
leucine rich repeat and Ig domain containing 2ENSG00000174482LINGO2chr9:27948078-28670286:-57.5
solute carrier family 46 member 2ENSG00000119457SLC46A2chr9:112878920-112890913:-56.5
TNF superfamily member 15ENSG00000181634TNFSF15chr9:114784635-114806126:-56.5
TNF superfamily member 8ENSG00000106952TNFSF8chr9:114893343-114930595:-57.5
toll like receptor 7ENSG00000196664TLR7chrX:12867083-12890380:+67.5
magnesium transporter 1ENSG00000102158MAGT1chrX:77826364-77895593:-612.5
ATPase Na+/K+ transporting family member beta 4ENSG00000101892ATP1B4chrX:120362085-120383249:+67.5
adhesion G protein-coupled receptor G4ENSG00000156920ADGRG4chrX:136300963-136416888:+68
CD99 molecule like 2ENSG00000102181CD99L2chrX:150766337-150898816:-512.5
microtubule actin crosslinking factor 1ENSG00000127603MACF1chr1:39081316-39487177:+511
chromosome 1 open reading frame 210ENSG00000253313C1orf210chr1:43281883-43285617:-56.5
EF-hand calcium binding domain 14ENSG00000159658EFCAB14chr1:46675159-46719064:-57.5
solute carrier family 5 member 9ENSG00000117834SLC5A9chr1:48222685-48248644:+67.5
solute carrier family 1 member 7ENSG00000162383SLC1A7chr1:53087179-53142632:-56.5

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