GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
transmembrane protein 184A | ENSG00000164855 | TMEM184A | chr7:1542235-1560821:- | 5 | 7 |
calneuron 1 | ENSG00000183166 | CALN1 | chr7:71779491-72447151:- | 5 | 6.5 |
leucine rich repeat containing 4 | ENSG00000128594 | LRRC4 | chr7:128027071-128032107:- | 5 | 6.5 |
EPH receptor B6 | ENSG00000106123 | EPHB6 | chr7:142855061-142871094:+ | 6 | 8.5 |
ADAM metallopeptidase domain 2 | ENSG00000104755 | ADAM2 | chr8:39743735-39838289:- | 5 | 6.5 |
sodium/potassium transporting ATPase interacting 3 | ENSG00000185942 | NKAIN3 | chr8:62248591-62999652:+ | 5 | 6.5 |
leucine rich repeat and Ig domain containing 2 | ENSG00000174482 | LINGO2 | chr9:27948078-28670286:- | 5 | 7.5 |
solute carrier family 46 member 2 | ENSG00000119457 | SLC46A2 | chr9:112878920-112890913:- | 5 | 6.5 |
TNF superfamily member 15 | ENSG00000181634 | TNFSF15 | chr9:114784635-114806126:- | 5 | 6.5 |
TNF superfamily member 8 | ENSG00000106952 | TNFSF8 | chr9:114893343-114930595:- | 5 | 7.5 |
toll like receptor 7 | ENSG00000196664 | TLR7 | chrX:12867083-12890380:+ | 6 | 7.5 |
magnesium transporter 1 | ENSG00000102158 | MAGT1 | chrX:77826364-77895593:- | 6 | 12.5 |
ATPase Na+/K+ transporting family member beta 4 | ENSG00000101892 | ATP1B4 | chrX:120362085-120383249:+ | 6 | 7.5 |
adhesion G protein-coupled receptor G4 | ENSG00000156920 | ADGRG4 | chrX:136300963-136416888:+ | 6 | 8 |
CD99 molecule like 2 | ENSG00000102181 | CD99L2 | chrX:150766337-150898816:- | 5 | 12.5 |
microtubule actin crosslinking factor 1 | ENSG00000127603 | MACF1 | chr1:39081316-39487177:+ | 5 | 11 |
chromosome 1 open reading frame 210 | ENSG00000253313 | C1orf210 | chr1:43281883-43285617:- | 5 | 6.5 |
EF-hand calcium binding domain 14 | ENSG00000159658 | EFCAB14 | chr1:46675159-46719064:- | 5 | 7.5 |
solute carrier family 5 member 9 | ENSG00000117834 | SLC5A9 | chr1:48222685-48248644:+ | 6 | 7.5 |
solute carrier family 1 member 7 | ENSG00000162383 | SLC1A7 | chr1:53087179-53142632:- | 5 | 6.5 |
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