GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
interleukin 17 receptor EENSG00000163701IL17REchr3:9902612-9916402:+56.5
solute carrier family 22 member 14ENSG00000144671SLC22A14chr3:38282294-38318575:+56.5
solute carrier family 6 member 20ENSG00000163817SLC6A20chr3:45755450-45796535:-67.5
potassium calcium-activated channel subfamily M regulatory beta subunit 2ENSG00000197584KCNMB2chr3:178272932-178844429:+67.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3ENSG00000171121KCNMB3chr3:179236691-179267002:-67.5
negative regulator of reactive oxygen speciesENSG00000174004NRROSchr3:196639686-196662004:+56.5
toll like receptor 10ENSG00000174123TLR10chr4:38772239-38782990:-68.5
epithelial mitogenENSG00000182585EPGNchr4:74308473-74315307:+56.5
sphingomyelin synthase 2ENSG00000164023SGMS2chr4:107824563-107915047:+68.5
ADAM metallopeptidase domain 29ENSG00000168594ADAM29chr4:174829668-174978180:+56.5
claudin 24ENSG00000185758CLDN24chr4:183321764-183322426:-67.5
prolactin receptorENSG00000113494PRLRchr5:35048756-35230589:-67.5
lectin, mannose binding 2ENSG00000169223LMAN2chr5:177331562-177351852:-612.5
leucine rich repeat and fibronectin type III domain containing 2ENSG00000156564LRFN2chr6:40391586-40587465:-57.5
meprin A subunit alphaENSG00000112818MEP1Achr6:46793390-46839782:+56.5
melanocortin 2 receptor accessory protein 2ENSG00000135324MRAP2chr6:84033756-84090881:+56.5
gap junction protein beta 7ENSG00000164411GJB7chr6:87282978-87329278:-67.5
triadinENSG00000186439TRDNchr6:123216339-123637093:-56.5
retinoic acid early transcript 1EENSG00000164520RAET1Echr6:149883375-149898102:-67.5
UL16 binding protein 1ENSG00000111981ULBP1chr6:149964007-149973710:+67.5

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