GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
solute carrier family 13 member 2 | ENSG00000007216 | SLC13A2 | chr17:28473293-28497781:+ | 5 | 7 |
ADAM metallopeptidase domain 11 | ENSG00000073670 | ADAM11 | chr17:44759031-44781846:+ | 5 | 6.5 |
DCC netrin 1 receptor | ENSG00000187323 | DCC | chr18:52340172-53535903:+ | 5 | 6.5 |
cation channel sperm associated auxiliary subunit delta | ENSG00000174898 | CATSPERD | chr19:5720677-5778734:+ | 5 | 6.5 |
C-type lectin domain family 4 member G | ENSG00000182566 | CLEC4G | chr19:7728957-7733906:- | 5 | 6.5 |
solute carrier family 1 member 6 | ENSG00000105143 | SLC1A6 | chr19:14950034-15022990:- | 5 | 6.5 |
GRAM domain containing 1A | ENSG00000089351 | GRAMD1A | chr19:34994784-35026471:+ | 5 | 8.5 |
CEA cell adhesion molecule 4 | ENSG00000105352 | CEACAM4 | chr19:41618971-41627074:- | 5 | 6.5 |
CEA cell adhesion molecule 20 | ENSG00000273777 | CEACAM20 | chr19:44501677-44529788:- | 5 | 6.5 |
solute carrier family 8 member A2 | ENSG00000118160 | SLC8A2 | chr19:47428017-47472168:- | 5 | 6.5 |
izumo sperm-egg fusion 1 | ENSG00000182264 | IZUMO1 | chr19:48740852-48746909:- | 5 | 6.5 |
myeloid associated differentiation marker | ENSG00000179820 | MYADM | chr19:53866223-53876437:+ | 5 | 12.5 |
ectodysplasin A receptor | ENSG00000135960 | EDAR | chr2:108894471-108989372:- | 6 | 7.5 |
LY6/PLAUR domain containing 6B | ENSG00000150556 | LYPD6B | chr2:149038107-149215262:+ | 5 | 7.5 |
histocompatibility minor 13 | ENSG00000101294 | HM13 | chr20:31514428-31577923:+ | 6 | 13.5 |
matrix metallopeptidase 24 | ENSG00000125966 | MMP24 | chr20:35226654-35277000:+ | 5 | 6.5 |
serine incorporator 3 | ENSG00000132824 | SERINC3 | chr20:44496221-44522109:- | 5 | 9.5 |
XK related 3 | ENSG00000172967 | XKR3 | chr22:16783412-16821699:- | 5 | 6.5 |
calcium voltage-gated channel auxiliary subunit gamma 2 | ENSG00000166862 | CACNG2 | chr22:36563921-36703558:- | 6 | 8.5 |
uroplakin 3A | ENSG00000100373 | UPK3A | chr22:45284982-45295874:+ | 5 | 6.5 |
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