GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
synaptotagmin 8 | ENSG00000149043 | SYT8 | chr11:1828307-1837521:+ | 6 | 7.5 |
cholinergic receptor nicotinic alpha 10 subunit | ENSG00000129749 | CHRNA10 | chr11:3665587-3671384:- | 6 | 7.5 |
leucine rich repeat containing 4C | ENSG00000148948 | LRRC4C | chr11:40114203-41459773:- | 5 | 6.5 |
solute carrier family 22 member 9 | ENSG00000149742 | SLC22A9 | chr11:63369789-63410294:+ | 5 | 6.5 |
V-set and transmembrane domain containing 5 | ENSG00000214376 | VSTM5 | chr11:93818232-93850531:- | 5 | 6.5 |
cytotoxic and regulatory T cell molecule | ENSG00000109943 | CRTAM | chr11:122838500-122872639:+ | 5 | 6.5 |
sodium voltage-gated channel beta subunit 3 | ENSG00000166257 | SCN3B | chr11:123629187-123655244:- | 6 | 7.5 |
V-set and immunoglobulin domain containing 2 | ENSG00000019102 | VSIG2 | chr11:124747472-124752238:- | 5 | 6.5 |
ATP binding cassette subfamily C member 9 | ENSG00000069431 | ABCC9 | chr12:21797401-21941402:- | 5 | 8 |
small cell adhesion glycoprotein | ENSG00000170545 | SMAGP | chr12:51244558-51270890:- | 5 | 6.5 |
GLI pathogenesis related 1 | ENSG00000139278 | GLIPR1 | chr12:75480680-75503853:+ | 5 | 9.5 |
stomatin like 3 | ENSG00000133115 | STOML3 | chr13:38965925-38991066:- | 5 | 6.5 |
transmembrane 9 superfamily member 2 | ENSG00000125304 | TM9SF2 | chr13:99501417-99564006:+ | 5 | 11.5 |
armadillo like helical domain containing 4 | ENSG00000139971 | C14orf37 | chr14:57999735-58298139:- | 5 | 6.5 |
potassium two pore domain channel subfamily K member 10 | ENSG00000100433 | KCNK10 | chr14:88180103-88326907:- | 6 | 9.5 |
leukocyte receptor tyrosine kinase | ENSG00000062524 | LTK | chr15:41503638-41513887:- | 6 | 7.5 |
synaptosome associated protein 23 | ENSG00000092531 | SNAP23 | chr15:42491233-42545356:+ | 6 | 12.5 |
tryptase gamma 1 | ENSG00000116176 | TPSG1 | chr16:1221651-1225257:- | 5 | 6.5 |
immunoglobulin superfamily member 6 | ENSG00000140749 | IGSF6 | chr16:21639537-21652660:- | 5 | 6.5 |
contactin associated protein family member 4 | ENSG00000152910 | CNTNAP4 | chr16:76277278-76559238:+ | 5 | 6.5 |
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