GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
protocadherin alpha 8ENSG00000204962PCDHA8chr5:140841187-141012344:+67.5
protocadherin alpha 9ENSG00000204961PCDHA9chr5:140847463-141012344:+67.5
protocadherin alpha 13ENSG00000239389PCDHA13chr5:140882208-141012344:+67.5
gamma-aminobutyric acid type A receptor subunit gamma2ENSG00000113327GABRG2chr5:162067540-162155536:+68.5
endogenous retrovirus group FRD member 1, envelopeENSG00000244476ERVFRD-1chr6:11102489-11111732:-56.5
mucin like 3ENSG00000168631DPCR1chr6:30940972-30954221:+57
major histocompatibility complex, class II, DM alphaENSG00000204257HLA-DMAchr6:32948613-32969094:-59
adhesion G protein-coupled receptor F4ENSG00000153294ADGRF4chr6:47685864-47722021:+57
endogenous retrovirus group W member 1, envelopeENSG00000242950ERVW-1chr7:92468380-92477986:-56.5
opsin 1, short wave sensitiveENSG00000128617OPN1SWchr7:128772491-128775790:-68
interleukin 11 receptor subunit alphaENSG00000137070IL11RAchr9:34650702-34661892:+68
stomatinENSG00000148175STOMchr9:121338988-121370304:-512.5
adhesion G protein-coupled receptor D2ENSG00000180264ADGRD2chr9:124451600-124478589:+68
ectodysplasin AENSG00000158813EDAchrX:69616067-70039469:+56.5
opsin 1, long wave sensitiveENSG00000102076OPN1LWchrX:154144224-154159032:+68
TNF receptor superfamily member 4ENSG00000186827TNFRSF4chr1:1211326-1214138:-56.5
solute carrier family 2 member 7ENSG00000197241SLC2A7chr1:9003300-9026345:-57.5
EPH receptor A8ENSG00000070886EPHA8chr1:22563564-22603594:+67.5
transmembrane and immunoglobulin domain containing 3ENSG00000121933ADORA3chr1:111483348-111563962:-57
insulin receptor related receptorENSG00000027644INSRRchr1:156840063-156859018:-67.5

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