GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
aquaporin 10ENSG00000143595AQP10chr1:154321090-154325325:+58.5
immunoglobulin superfamily member 9ENSG00000085552IGSF9chr1:159927039-159945604:-67.5
opsin 3ENSG00000054277OPN3chr1:241590102-241677376:-68
cadherin related family member 1ENSG00000148600CDHR1chr10:84194635-84219621:+67.5
immunoglobulin superfamily member 9BENSG00000080854IGSF9Bchr11:133908564-133956985:-56.5
neurexin 3ENSG00000021645NRXN3chr14:78242391-79868290:+510
immunoglobulin superfamily containing leucine rich repeat 2ENSG00000167178ISLR2chr15:74100311-74138540:+56.5
glycoprotein 2ENSG00000169347GP2chr16:20309572-20327808:-56.5
linker for activation of T cellsENSG00000213658LATchr16:28984826-28990783:+69
thyroid peroxidaseENSG00000115705TPOchr2:1374223-1543711:+57
activin A receptor type 1CENSG00000123612ACVR1Cchr2:157526767-157629005:-67.5
receptor activity modifying protein 1ENSG00000132329RAMP1chr2:237858893-237912114:+68.5
beta-secretase 2ENSG00000182240BACE2chr21:41167801-41282518:+67.5
NFAT activating protein with ITAM motif 1ENSG00000235568NFAM1chr22:42380410-42432395:-56.5
adhesion G protein-coupled receptor G7ENSG00000144820ADGRG7chr3:100609589-100695479:+68
ADP-ribosyltransferase 3ENSG00000156219ART3chr4:76011184-76112802:+56.5
retinal pigment epithelium-derived rhodopsin homologENSG00000180245RRHchr4:109827994-109844604:+68
protocadherin alpha 2ENSG00000204969PCDHA2chr5:140794852-141012344:+68.5
protocadherin alpha 5ENSG00000204965PCDHA5chr5:140821604-141012344:+67.5
protocadherin alpha 7ENSG00000204963PCDHA7chr5:140834248-141012344:+67.5

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