GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
aquaporin 10 | ENSG00000143595 | AQP10 | chr1:154321090-154325325:+ | 5 | 8.5 |
immunoglobulin superfamily member 9 | ENSG00000085552 | IGSF9 | chr1:159927039-159945604:- | 6 | 7.5 |
opsin 3 | ENSG00000054277 | OPN3 | chr1:241590102-241677376:- | 6 | 8 |
cadherin related family member 1 | ENSG00000148600 | CDHR1 | chr10:84194635-84219621:+ | 6 | 7.5 |
immunoglobulin superfamily member 9B | ENSG00000080854 | IGSF9B | chr11:133908564-133956985:- | 5 | 6.5 |
neurexin 3 | ENSG00000021645 | NRXN3 | chr14:78242391-79868290:+ | 5 | 10 |
immunoglobulin superfamily containing leucine rich repeat 2 | ENSG00000167178 | ISLR2 | chr15:74100311-74138540:+ | 5 | 6.5 |
glycoprotein 2 | ENSG00000169347 | GP2 | chr16:20309572-20327808:- | 5 | 6.5 |
linker for activation of T cells | ENSG00000213658 | LAT | chr16:28984826-28990783:+ | 6 | 9 |
thyroid peroxidase | ENSG00000115705 | TPO | chr2:1374223-1543711:+ | 5 | 7 |
activin A receptor type 1C | ENSG00000123612 | ACVR1C | chr2:157526767-157629005:- | 6 | 7.5 |
receptor activity modifying protein 1 | ENSG00000132329 | RAMP1 | chr2:237858893-237912114:+ | 6 | 8.5 |
beta-secretase 2 | ENSG00000182240 | BACE2 | chr21:41167801-41282518:+ | 6 | 7.5 |
NFAT activating protein with ITAM motif 1 | ENSG00000235568 | NFAM1 | chr22:42380410-42432395:- | 5 | 6.5 |
adhesion G protein-coupled receptor G7 | ENSG00000144820 | ADGRG7 | chr3:100609589-100695479:+ | 6 | 8 |
ADP-ribosyltransferase 3 | ENSG00000156219 | ART3 | chr4:76011184-76112802:+ | 5 | 6.5 |
retinal pigment epithelium-derived rhodopsin homolog | ENSG00000180245 | RRH | chr4:109827994-109844604:+ | 6 | 8 |
protocadherin alpha 2 | ENSG00000204969 | PCDHA2 | chr5:140794852-141012344:+ | 6 | 8.5 |
protocadherin alpha 5 | ENSG00000204965 | PCDHA5 | chr5:140821604-141012344:+ | 6 | 7.5 |
protocadherin alpha 7 | ENSG00000204963 | PCDHA7 | chr5:140834248-141012344:+ | 6 | 7.5 |
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