GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
G protein-coupled receptor 88 | ENSG00000181656 | GPR88 | chr1:100538137-100542018:+ | 6 | 8 |
opsin 4 | ENSG00000122375 | OPN4 | chr10:86654557-86666848:+ | 6 | 8 |
olfactory receptor family 5 subfamily AN member 1 | ENSG00000176495 | OR5AN1 | chr11:59364412-59365448:+ | 5 | 7 |
G protein-coupled receptor 162 | ENSG00000250510 | GPR162 | chr12:6821545-6829972:+ | 5 | 7 |
olfactory receptor family 11 subfamily H member 2 | ENSG00000258453 | OR11H2 | chr14:19712936-19713920:- | 5 | 7 |
prostaglandin D2 receptor | ENSG00000168229 | PTGDR | chr14:52267713-52276724:+ | 5 | 7 |
adhesion G protein-coupled receptor G5 | ENSG00000159618 | ADGRG5 | chr16:57542421-57591681:+ | 6 | 8 |
adhesion G protein-coupled receptor G3 | ENSG00000182885 | ADGRG3 | chr16:57668187-57689378:+ | 6 | 8 |
olfactory receptor family 1 subfamily D member 2 | ENSG00000184166 | OR1D2 | chr17:3092058-3092996:- | 5 | 7 |
G protein-coupled receptor 42 (gene/pseudogene) | ENSG00000126251 | GPR42 | chr19:35370929-35372962:+ | 5 | 7 |
formyl peptide receptor 1 | ENSG00000171051 | FPR1 | chr19:51745172-51804110:- | 5 | 8 |
G protein-coupled receptor 75 | ENSG00000119737 | GPR75 | chr2:53852913-53859989:- | 6 | 8 |
adrenoceptor alpha 2B | ENSG00000274286 | ADRA2B | chr2:96112875-96116245:- | 6 | 8 |
opioid receptor mu 1 | ENSG00000112038 | OPRM1 | chr6:154010496-154246867:+ | 6 | 8 |
G protein-coupled receptor 31 | ENSG00000120436 | GPR31 | chr6:167156271-167158329:- | 5 | 7 |
G protein-coupled receptor 22 | ENSG00000172209 | GPR22 | chr7:107470018-107475659:+ | 5 | 7 |
frizzled class receptor 3 | ENSG00000104290 | FZD3 | chr8:28494205-28574268:+ | 6 | 8 |
olfactory receptor family 2 subfamily S member 2 (gene/pseudogene) | ENSG00000278889 | OR2S2 | chr9:35957108-35958154:- | 5 | 7 |
G protein-coupled receptor 34 | ENSG00000171659 | GPR34 | chrX:41688973-41697277:+ | 5 | 7 |
arginine vasopressin receptor 2 | ENSG00000126895 | AVPR2 | chrX:153902531-153907166:+ | 6 | 8 |
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