GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
trace amine associated receptor 3, pseudogeneENSG00000179073TAAR3chr6:132608225-132609302:-66.5
annexin A1ENSG00000135046ANXA1chr9:73151757-73170393:+713
osteoglycinENSG00000106809OGNchr9:92383967-92404696:-67
hemicentin 1ENSG00000143341HMCN1chr1:185734551-186190949:+67
A-kinase anchoring protein 11ENSG00000023516AKAP11chr13:42272153-42323267:+67
natural killer cell triggering receptorENSG00000114857NKTRchr3:42600614-42648741:+66
ABI family member 3 binding proteinENSG00000154175ABI3BPchr3:100749156-100993515:-67.5
myristoylated alanine rich protein kinase C substrateENSG00000277443MARCKSchr6:113857362-113863471:+68
cathepsin VENSG00000136943CTSVchr9:97029679-97039643:-66
olfactomedin 1ENSG00000130558OLFM1chr9:135075243-135121179:+66
dipeptidyl peptidase 7ENSG00000176978DPP7chr9:137110542-137115177:-611.5
matrix remodeling associated 5ENSG00000101825MXRA5chrX:3308565-3346641:-67
proline and arginine rich end leucine rich repeat proteinENSG00000188783PRELPchr1:203475828-203491352:+66
tolloid like 2ENSG00000095587TLL2chr10:96364606-96513918:-66
collagen type VI alpha 3 chainENSG00000163359COL6A3chr2:237324003-237414375:-610
signal peptide, CUB domain and EGF like domain containing 3ENSG00000146197SCUBE3chr6:35214419-35253079:+66
neuronal pentraxin 2ENSG00000106236NPTX2chr7:98617297-98629868:+66
TNF receptor superfamily member 11bENSG00000164761TNFRSF11Bchr8:118923557-118952200:-67
dopamine receptor D2ENSG00000149295DRD2chr11:113409615-113475691:-69
melanocortin 4 receptorENSG00000166603MC4Rchr18:60371110-60372775:-58

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