GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
trace amine associated receptor 3, pseudogene | ENSG00000179073 | TAAR3 | chr6:132608225-132609302:- | 6 | 6.5 |
annexin A1 | ENSG00000135046 | ANXA1 | chr9:73151757-73170393:+ | 7 | 13 |
osteoglycin | ENSG00000106809 | OGN | chr9:92383967-92404696:- | 6 | 7 |
hemicentin 1 | ENSG00000143341 | HMCN1 | chr1:185734551-186190949:+ | 6 | 7 |
A-kinase anchoring protein 11 | ENSG00000023516 | AKAP11 | chr13:42272153-42323267:+ | 6 | 7 |
natural killer cell triggering receptor | ENSG00000114857 | NKTR | chr3:42600614-42648741:+ | 6 | 6 |
ABI family member 3 binding protein | ENSG00000154175 | ABI3BP | chr3:100749156-100993515:- | 6 | 7.5 |
myristoylated alanine rich protein kinase C substrate | ENSG00000277443 | MARCKS | chr6:113857362-113863471:+ | 6 | 8 |
cathepsin V | ENSG00000136943 | CTSV | chr9:97029679-97039643:- | 6 | 6 |
olfactomedin 1 | ENSG00000130558 | OLFM1 | chr9:135075243-135121179:+ | 6 | 6 |
dipeptidyl peptidase 7 | ENSG00000176978 | DPP7 | chr9:137110542-137115177:- | 6 | 11.5 |
matrix remodeling associated 5 | ENSG00000101825 | MXRA5 | chrX:3308565-3346641:- | 6 | 7 |
proline and arginine rich end leucine rich repeat protein | ENSG00000188783 | PRELP | chr1:203475828-203491352:+ | 6 | 6 |
tolloid like 2 | ENSG00000095587 | TLL2 | chr10:96364606-96513918:- | 6 | 6 |
collagen type VI alpha 3 chain | ENSG00000163359 | COL6A3 | chr2:237324003-237414375:- | 6 | 10 |
signal peptide, CUB domain and EGF like domain containing 3 | ENSG00000146197 | SCUBE3 | chr6:35214419-35253079:+ | 6 | 6 |
neuronal pentraxin 2 | ENSG00000106236 | NPTX2 | chr7:98617297-98629868:+ | 6 | 6 |
TNF receptor superfamily member 11b | ENSG00000164761 | TNFRSF11B | chr8:118923557-118952200:- | 6 | 7 |
dopamine receptor D2 | ENSG00000149295 | DRD2 | chr11:113409615-113475691:- | 6 | 9 |
melanocortin 4 receptor | ENSG00000166603 | MC4R | chr18:60371110-60372775:- | 5 | 8 |
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