GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
major histocompatibility complex, class I, H (pseudogene)ENSG00000206341HLA-Hchr6:29887752-29890482:+710
T cell receptor gamma constant 2ENSG00000227191TRGC2chr7:38239580-38368091:-66
olfactory receptor family 10 subfamily AC member 1 (gene/pseudogene)ENSG00000176510OR10AC1chr7:143510933-143511911:-66.5
olfactory receptor family 51 subfamily G member 1 (gene/pseudogene)ENSG00000278870OR51G1chr11:4923301-4924407:-77
radixinENSG00000137710RDXchr11:110174880-110296722:-69
glyceraldehyde-3-phosphate dehydrogenaseENSG00000111640GAPDHchr12:6533927-6538374:+613
LIM domain and actin binding 1ENSG00000050405LIMA1chr12:50175788-50283546:-611
neurexophilin 4ENSG00000182379NXPH4chr12:57216795-57226449:+66
cathepsin GENSG00000100448CTSGchr14:24573522-24576260:-67
immunoglobulin heavy constant muENSG00000211899IGHMchr14:105854220-106235572:-710
endogenous retrovirus group K13 member 1ENSG00000260565CTD-2270P14.1chr16:2660349-2673444:-66
olfactory receptor family 1 subfamily F member 2 pseudogeneENSG00000203581OR1F2Pchr16:3215611-3216543:+66
cytohesin 1ENSG00000108669CYTH1chr17:78674048-78782297:-68
endogenous retrovirus group K9, member 11ENSG00000269486CTC-360G5.9chr19:38935297-38938632:-66
adenosine deaminaseENSG00000196839ADAchr20:44619522-44652233:-610
neurofibromin 2ENSG00000186575NF2chr22:29603556-29698598:+67
ceruloplasminENSG00000047457CPchr3:149162410-149222055:-710.5
versicanENSG00000038427VCANchr5:83471465-83582303:+69
protocadherin beta 18 pseudogeneENSG00000146001PCDHB18Pchr5:141234333-141237529:+77
C1q and TNF related 2ENSG00000145861C1QTNF2chr5:160347751-160370641:-66.5

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