GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
coiled-coil domain containing 126ENSG00000169193CCDC126chr7:23597379-23644708:+69
phospholipase B domain containing 2ENSG00000151176PLBD2chr12:113358566-113391625:+68
serpin family A member 5ENSG00000188488SERPINA5chr14:94561442-94593120:+67.5
phospholipid scramblase 1ENSG00000188313PLSCR1chr3:146515180-146544864:-78
LDL receptor related protein associated protein 1ENSG00000163956LRPAP1chr4:3506376-3532559:-611.5
tolloid like 1ENSG00000038295TLL1chr4:165873258-166103895:+66.5
chromosome 6 open reading frame 120ENSG00000185127C6orf120chr6:169702190-169704856:+66.5
gonadotropin releasing hormone receptor 2 (pseudogene)ENSG00000211451GNRHR2chr1:145919013-145925341:+77.5
Fc fragment of IgG receptor IIc (gene/pseudogene)ENSG00000244682FCGR2Cchr1:161581339-161605662:+67
olfactomedin like 2BENSG00000162745OLFML2Bchr1:161983192-162023854:-66.5
olfactory receptor family 14 subfamily L member 1 pseudogeneENSG00000198452OR14L1Pchr1:247619643-247620570:+66.5
olfactory receptor family 2 subfamily T member 11 (gene/pseudogene)ENSG00000279301OR2T11chr1:248626119-248627190:-66.5
supervillinENSG00000197321SVILchr10:29457338-29736781:-68
ankyrin 3ENSG00000151150ANK3chr10:60026298-60733490:-79
olfactory receptor family 52 subfamily B member 4 (gene/pseudogene)ENSG00000221996OR52B4chr11:4367263-4368386:-77.5
olfactory receptor family 52 subfamily A member 4 pseudogeneENSG00000205494OR52A4Pchr11:5120621-5124513:-77.5
olfactory receptor family 52 subfamily Z member 1 (gene/pseudogene)ENSG00000176748OR52Z1chr11:5177714-5178610:-77.5
olfactory receptor family 51 subfamily B member 2 (gene/pseudogene)ENSG00000279012OR51B2chr11:5323311-5324352:-77.5
olfactory receptor family 52 subfamily P member 1 pseudogeneENSG00000181109OR52P1Pchr11:5726502-5727464:+77.5
olfactory receptor family 52 subfamily L member 2 pseudogeneENSG00000262980OR52L2Pchr11:6057316-6058275:-77.5

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