GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
coiled-coil domain containing 126 | ENSG00000169193 | CCDC126 | chr7:23597379-23644708:+ | 6 | 9 |
phospholipase B domain containing 2 | ENSG00000151176 | PLBD2 | chr12:113358566-113391625:+ | 6 | 8 |
serpin family A member 5 | ENSG00000188488 | SERPINA5 | chr14:94561442-94593120:+ | 6 | 7.5 |
phospholipid scramblase 1 | ENSG00000188313 | PLSCR1 | chr3:146515180-146544864:- | 7 | 8 |
LDL receptor related protein associated protein 1 | ENSG00000163956 | LRPAP1 | chr4:3506376-3532559:- | 6 | 11.5 |
tolloid like 1 | ENSG00000038295 | TLL1 | chr4:165873258-166103895:+ | 6 | 6.5 |
chromosome 6 open reading frame 120 | ENSG00000185127 | C6orf120 | chr6:169702190-169704856:+ | 6 | 6.5 |
gonadotropin releasing hormone receptor 2 (pseudogene) | ENSG00000211451 | GNRHR2 | chr1:145919013-145925341:+ | 7 | 7.5 |
Fc fragment of IgG receptor IIc (gene/pseudogene) | ENSG00000244682 | FCGR2C | chr1:161581339-161605662:+ | 6 | 7 |
olfactomedin like 2B | ENSG00000162745 | OLFML2B | chr1:161983192-162023854:- | 6 | 6.5 |
olfactory receptor family 14 subfamily L member 1 pseudogene | ENSG00000198452 | OR14L1P | chr1:247619643-247620570:+ | 6 | 6.5 |
olfactory receptor family 2 subfamily T member 11 (gene/pseudogene) | ENSG00000279301 | OR2T11 | chr1:248626119-248627190:- | 6 | 6.5 |
supervillin | ENSG00000197321 | SVIL | chr10:29457338-29736781:- | 6 | 8 |
ankyrin 3 | ENSG00000151150 | ANK3 | chr10:60026298-60733490:- | 7 | 9 |
olfactory receptor family 52 subfamily B member 4 (gene/pseudogene) | ENSG00000221996 | OR52B4 | chr11:4367263-4368386:- | 7 | 7.5 |
olfactory receptor family 52 subfamily A member 4 pseudogene | ENSG00000205494 | OR52A4P | chr11:5120621-5124513:- | 7 | 7.5 |
olfactory receptor family 52 subfamily Z member 1 (gene/pseudogene) | ENSG00000176748 | OR52Z1 | chr11:5177714-5178610:- | 7 | 7.5 |
olfactory receptor family 51 subfamily B member 2 (gene/pseudogene) | ENSG00000279012 | OR51B2 | chr11:5323311-5324352:- | 7 | 7.5 |
olfactory receptor family 52 subfamily P member 1 pseudogene | ENSG00000181109 | OR52P1P | chr11:5726502-5727464:+ | 7 | 7.5 |
olfactory receptor family 52 subfamily L member 2 pseudogene | ENSG00000262980 | OR52L2P | chr11:6057316-6058275:- | 7 | 7.5 |
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