GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
ectonucleoside triphosphate diphosphohydrolase 2ENSG00000054179ENTPD2chr9:137048098-137054045:-68.5
calcium voltage-gated channel subunit alpha1 FENSG00000102001CACNA1FchrX:49205063-49233371:-67.5
V-set and immunoglobulin domain containing 4ENSG00000155659VSIG4chrX:66021738-66040125:-68.5
proton activated chloride channel 1ENSG00000065600TMEM206chr1:212363931-212414901:-612.5
gliomedinENSG00000186417GLDNchr15:51341629-51408013:+66.5
TM2 domain containing 3ENSG00000184277TM2D3chr15:101621444-101652391:-69.5
phosphatidylinositol glycan anchor biosynthesis class NENSG00000197563PIGNchr18:62043567-62187118:-79.5
CD177 moleculeENSG00000204936CD177chr19:43353659-43363172:+66.5
solute carrier family 23 member 3ENSG00000213901SLC23A3chr2:219161465-219170095:-68.5
zinc finger DHHC-type palmitoyltransferase 23ENSG00000184307ZDHHC23chr3:113947901-113965401:+78.5
ectonucleotide pyrophosphatase/phosphodiesterase 6ENSG00000164303ENPP6chr4:184088706-184221230:-77.5
UL16 binding protein 3ENSG00000131019ULBP3chr6:150063150-150069095:-79.5
acid sensing ion channel subunit 3ENSG00000213199ASIC3chr7:151048292-151052756:+67
CUB and Sushi multiple domains 3ENSG00000164796CSMD3chr8:112222928-113437099:-67.5
neural proliferation, differentiation and control 1ENSG00000107281NPDC1chr9:137039470-137046203:-67
arylsulfatase FENSG00000062096ARSFchrX:3041471-3112726:+67.5
actinin alpha 1ENSG00000072110ACTN1chr14:68874143-68979440:-610.5
glucose-6-phosphate isomeraseENSG00000105220GPIchr19:34359480-34402156:+612.5
GDNF family receptor alpha 4ENSG00000125861GFRA4chr20:3659292-3663399:-77
fibroblast growth factor 10ENSG00000070193FGF10chr5:44303544-44389706:-67

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