GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
collectin subfamily member 12 | ENSG00000158270 | COLEC12 | chr18:316740-500722:- | 6 | 11.5 |
G protein-coupled receptor 108 | ENSG00000125734 | GPR108 | chr19:6729914-6737603:- | 6 | 10.5 |
leucine rich repeat containing 8 VRAC subunit E | ENSG00000171017 | LRRC8E | chr19:7888505-7902021:+ | 6 | 8.5 |
potassium two pore domain channel subfamily K member 6 | ENSG00000099337 | KCNK6 | chr19:38319844-38332076:+ | 7 | 10.5 |
CEA cell adhesion molecule 7 | ENSG00000007306 | CEACAM7 | chr19:41673307-41706976:- | 6 | 7 |
hyaluronan synthase 1 | ENSG00000105509 | HAS1 | chr19:51713112-51723994:- | 7 | 9.5 |
potassium two pore domain channel subfamily K member 3 | ENSG00000171303 | KCNK3 | chr2:26692690-26733420:+ | 7 | 9.5 |
prion like protein doppel | ENSG00000171864 | PRND | chr20:4721910-4728460:+ | 6 | 7 |
calcium voltage-gated channel subunit alpha1 D | ENSG00000157388 | CACNA1D | chr3:53494656-53813733:+ | 6 | 7.5 |
neutral cholesterol ester hydrolase 1 | ENSG00000144959 | NCEH1 | chr3:172630249-172711218:- | 6 | 13.5 |
dachsous cadherin-related 2 | ENSG00000197410 | DCHS2 | chr4:154232037-154491716:- | 6 | 7.5 |
solute carrier family 17 member 4 | ENSG00000146039 | SLC17A4 | chr6:25754699-25781191:+ | 6 | 7.5 |
calcium voltage-gated channel auxiliary subunit alpha2delta 1 | ENSG00000153956 | CACNA2D1 | chr7:81946444-82443798:- | 7 | 11 |
tetraspanin 12 | ENSG00000106025 | TSPAN12 | chr7:120787320-120858402:- | 7 | 8.5 |
solute carrier family 10 member 5 | ENSG00000253598 | SLC10A5 | chr8:81693607-81696174:- | 6 | 7.5 |
potassium voltage-gated channel modifier subfamily V member 1 | ENSG00000164794 | KCNV1 | chr8:109963645-109975847:- | 7 | 8.5 |
adenylate cyclase 8 | ENSG00000155897 | ADCY8 | chr8:130780301-131042426:- | 7 | 8.5 |
potassium two pore domain channel subfamily K member 9 | ENSG00000169427 | KCNK9 | chr8:139600838-139703056:- | 7 | 8.5 |
endoplasmic reticulum metallopeptidase 1 | ENSG00000099219 | ERMP1 | chr9:5765076-5833117:- | 6 | 10.5 |
potassium sodium-activated channel subfamily T member 1 | ENSG00000107147 | KCNT1 | chr9:135702185-135795508:+ | 7 | 9.5 |
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