GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
collectin subfamily member 12ENSG00000158270COLEC12chr18:316740-500722:-611.5
G protein-coupled receptor 108ENSG00000125734GPR108chr19:6729914-6737603:-610.5
leucine rich repeat containing 8 VRAC subunit EENSG00000171017LRRC8Echr19:7888505-7902021:+68.5
potassium two pore domain channel subfamily K member 6ENSG00000099337KCNK6chr19:38319844-38332076:+710.5
CEA cell adhesion molecule 7ENSG00000007306CEACAM7chr19:41673307-41706976:-67
hyaluronan synthase 1ENSG00000105509HAS1chr19:51713112-51723994:-79.5
potassium two pore domain channel subfamily K member 3ENSG00000171303KCNK3chr2:26692690-26733420:+79.5
prion like protein doppelENSG00000171864PRNDchr20:4721910-4728460:+67
calcium voltage-gated channel subunit alpha1 DENSG00000157388CACNA1Dchr3:53494656-53813733:+67.5
neutral cholesterol ester hydrolase 1ENSG00000144959NCEH1chr3:172630249-172711218:-613.5
dachsous cadherin-related 2ENSG00000197410DCHS2chr4:154232037-154491716:-67.5
solute carrier family 17 member 4ENSG00000146039SLC17A4chr6:25754699-25781191:+67.5
calcium voltage-gated channel auxiliary subunit alpha2delta 1ENSG00000153956CACNA2D1chr7:81946444-82443798:-711
tetraspanin 12ENSG00000106025TSPAN12chr7:120787320-120858402:-78.5
solute carrier family 10 member 5ENSG00000253598SLC10A5chr8:81693607-81696174:-67.5
potassium voltage-gated channel modifier subfamily V member 1ENSG00000164794KCNV1chr8:109963645-109975847:-78.5
adenylate cyclase 8ENSG00000155897ADCY8chr8:130780301-131042426:-78.5
potassium two pore domain channel subfamily K member 9ENSG00000169427KCNK9chr8:139600838-139703056:-78.5
endoplasmic reticulum metallopeptidase 1ENSG00000099219ERMP1chr9:5765076-5833117:-610.5
potassium sodium-activated channel subfamily T member 1ENSG00000107147KCNT1chr9:135702185-135795508:+79.5

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