GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
major facilitator superfamily domain containing 4AENSG00000174514MFSD4chr1:205568885-205602918:+67.5
gap junction protein delta 4ENSG00000177291GJD4chr10:35605410-35608935:+78.5
N-acylsphingosine amidohydrolase 2ENSG00000188611ASAH2chr10:50182778-50248610:-67.5
transmembrane protein 26ENSG00000196932TMEM26chr10:61406643-61453450:-67.5
transient receptor potential cation channel subfamily M member 5ENSG00000070985TRPM5chr11:2404515-2423045:-67.5
transmembrane protein 179BENSG00000185475TMEM179Bchr11:62787415-62790405:+69.5
pannexin 3ENSG00000154143PANX3chr11:124611490-124620356:+78.5
potassium voltage-gated channel subfamily A member 6ENSG00000151079KCNA6chr12:4809176-4813412:+78.5
NCK associated protein 1 likeENSG00000123338NCKAP1Lchr12:54497711-54548238:+712
solute carrier family 7 member 7ENSG00000155465SLC7A7chr14:22773222-22829820:-67.5
ATPase phospholipid transporting 10A (putative)ENSG00000206190ATP10Achr15:25677273-25865172:-710.5
transient receptor potential cation channel subfamily M member 1ENSG00000134160TRPM1chr15:31001061-31161273:-67.5
ATPase phospholipid transporting 8B4 (putative)ENSG00000104043ATP8B4chr15:49858238-50182817:-79.5
repulsive guidance molecule BMP co-receptor aENSG00000182175RGMAchr15:93035273-93089204:-79
ORAI calcium release-activated calcium modulator 3ENSG00000175938ORAI3chr16:30949066-30956461:+68
solute carrier family 47 member 2ENSG00000180638SLC47A2chr17:19678288-19718979:-67.5
oligodendrocyte myelin glycoproteinENSG00000126861OMGchr17:31272013-31297539:-78
ATP binding cassette subfamily A member 9ENSG00000154258ABCA9chr17:68974488-69061064:-67.5
ATP binding cassette subfamily A member 6ENSG00000154262ABCA6chr17:69078702-69141888:-69.5
ATP binding cassette subfamily A member 5ENSG00000154265ABCA5chr17:69244311-69327244:-79.5

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