GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
CD72 moleculeENSG00000137101CD72chr9:35609533-35646810:-610.5
transmembrane protein 8BENSG00000137103TMEM8Bchr9:35814451-35854847:+79.5
cell migration inducing hyaluronidase 2ENSG00000135048TMEM2chr9:71683366-71816690:-612.5
multiple EGF like domains 9ENSG00000106780MEGF9chr9:120600813-120714470:-69.5
solute carrier family 2 member 8ENSG00000136856SLC2A8chr9:127397138-127408424:+79.5
solute carrier family 2 member 6ENSG00000160326SLC2A6chr9:133471095-133479137:-78.5
toll like receptor 8ENSG00000101916TLR8chrX:12906620-12923169:+78.5
ectodysplasin A2 receptorENSG00000131080EDA2RchrX:66595637-66639298:-78.5
glycerophosphodiester phosphodiesterase domain containing 2ENSG00000130055GDPD2chrX:70423031-70433390:+67.5
ATPase copper transporting alphaENSG00000165240ATP7AchrX:77910656-78050395:+79.5
glycine receptor alpha 4 (pseudogene)ENSG00000188828GLRA4chrX:103707224-103728655:-78.5
proteolipid protein 1ENSG00000123560PLP1chrX:103773718-103792619:+78.5
potassium voltage-gated channel subfamily E regulatory subunit 5ENSG00000176076KCNE5chrX:109623700-109625172:-78.5
solute carrier family 9 member A6ENSG00000198689SLC9A6chrX:135985424-136047269:+710.5
leucine rich repeat containing 8 VRAC subunit BENSG00000197147LRRC8Bchr1:89524836-89597864:+68.5
potassium voltage-gated channel subfamily D member 3ENSG00000171385KCND3chr1:111770662-111989155:-78.5
hemojuvelin BMP co-receptorENSG00000168509HFE2chr1:146017468-146021918:-79.5
gap junction protein alpha 8ENSG00000121634GJA8chr1:147907956-147909257:+78.5
ephrin A3ENSG00000143590EFNA3chr1:155078872-155087538:+78
potassium inwardly rectifying channel subfamily J member 10ENSG00000177807KCNJ10chr1:160037467-160070248:-67.5

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