GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
LysM domain containing 3ENSG00000176018LYSMD3chr5:90515611-90529584:-68.5
peptidylglycine alpha-amidating monooxygenaseENSG00000145730PAMchr5:102753981-103031105:+710.5
protocadherin beta 16ENSG00000272674PCDHB16chr5:141181399-141186399:+78.5
solute carrier family 36 member 2ENSG00000186335SLC36A2chr5:151314978-151347590:-67.5
hepatitis A virus cellular receptor 2ENSG00000135077HAVCR2chr5:157085832-157142869:-68.5
inositol 1,4,5-trisphosphate receptor type 3ENSG00000096433ITPR3chr6:33620365-33696574:+714.5
solute carrier family 26 member 8ENSG00000112053SLC26A8chr6:35943514-36024868:-78.5
chromosome 6 open reading frame 89ENSG00000198663C6orf89chr6:36871870-36928964:+69.5
triggering receptor expressed on myeloid cells like 1ENSG00000161911TREML1chr6:41149342-41154337:-67.5
ATP binding cassette subfamily C member 10ENSG00000124574ABCC10chr6:43427366-43450430:+68.5
patched domain containing 4ENSG00000244694PTCHD4chr6:47878028-48068689:-68
Rh associated glycoproteinENSG00000112077RHAGchr6:49605158-49636839:-78.5
ROS proto-oncogene 1, receptor tyrosine kinaseENSG00000047936ROS1chr6:117288300-117425855:-78.5
solute carrier family 2 member 12ENSG00000146411SLC2A12chr6:133988697-134052636:-78.5
STEAP2 metalloreductaseENSG00000157214STEAP2chr7:90167590-90238137:+78.5
gap junction protein gamma 3ENSG00000176402GJC3chr7:99923269-99929620:-78.5
mucin 12, cell surface associatedENSG00000205277MUC12chr7:100969623-101018949:+67.5
TNF receptor superfamily member 10dENSG00000173530TNFRSF10Dchr8:23135588-23164030:-79.5
aspartate beta-hydroxylaseENSG00000198363ASPHchr8:61500556-61714640:-612.5
mal, T cell differentiation protein 2 (gene/pseudogene)ENSG00000147676MAL2chr8:119165034-119245673:+69.5

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