GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
LysM domain containing 3 | ENSG00000176018 | LYSMD3 | chr5:90515611-90529584:- | 6 | 8.5 |
peptidylglycine alpha-amidating monooxygenase | ENSG00000145730 | PAM | chr5:102753981-103031105:+ | 7 | 10.5 |
protocadherin beta 16 | ENSG00000272674 | PCDHB16 | chr5:141181399-141186399:+ | 7 | 8.5 |
solute carrier family 36 member 2 | ENSG00000186335 | SLC36A2 | chr5:151314978-151347590:- | 6 | 7.5 |
hepatitis A virus cellular receptor 2 | ENSG00000135077 | HAVCR2 | chr5:157085832-157142869:- | 6 | 8.5 |
inositol 1,4,5-trisphosphate receptor type 3 | ENSG00000096433 | ITPR3 | chr6:33620365-33696574:+ | 7 | 14.5 |
solute carrier family 26 member 8 | ENSG00000112053 | SLC26A8 | chr6:35943514-36024868:- | 7 | 8.5 |
chromosome 6 open reading frame 89 | ENSG00000198663 | C6orf89 | chr6:36871870-36928964:+ | 6 | 9.5 |
triggering receptor expressed on myeloid cells like 1 | ENSG00000161911 | TREML1 | chr6:41149342-41154337:- | 6 | 7.5 |
ATP binding cassette subfamily C member 10 | ENSG00000124574 | ABCC10 | chr6:43427366-43450430:+ | 6 | 8.5 |
patched domain containing 4 | ENSG00000244694 | PTCHD4 | chr6:47878028-48068689:- | 6 | 8 |
Rh associated glycoprotein | ENSG00000112077 | RHAG | chr6:49605158-49636839:- | 7 | 8.5 |
ROS proto-oncogene 1, receptor tyrosine kinase | ENSG00000047936 | ROS1 | chr6:117288300-117425855:- | 7 | 8.5 |
solute carrier family 2 member 12 | ENSG00000146411 | SLC2A12 | chr6:133988697-134052636:- | 7 | 8.5 |
STEAP2 metalloreductase | ENSG00000157214 | STEAP2 | chr7:90167590-90238137:+ | 7 | 8.5 |
gap junction protein gamma 3 | ENSG00000176402 | GJC3 | chr7:99923269-99929620:- | 7 | 8.5 |
mucin 12, cell surface associated | ENSG00000205277 | MUC12 | chr7:100969623-101018949:+ | 6 | 7.5 |
TNF receptor superfamily member 10d | ENSG00000173530 | TNFRSF10D | chr8:23135588-23164030:- | 7 | 9.5 |
aspartate beta-hydroxylase | ENSG00000198363 | ASPH | chr8:61500556-61714640:- | 6 | 12.5 |
mal, T cell differentiation protein 2 (gene/pseudogene) | ENSG00000147676 | MAL2 | chr8:119165034-119245673:+ | 6 | 9.5 |
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