GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
modulator of VRAC current 1ENSG00000100427MLC1chr22:50059391-50085902:-67.5
caveolin 3ENSG00000182533CAV3chr3:8733800-8841808:+78.5
solute carrier family 22 member 13ENSG00000172940SLC22A13chr3:38265812-38278315:+67.5
gamma-aminobutyric acid type A receptor subunit rho3 (gene/pseudogene)ENSG00000183185GABRR3chr3:97986673-98035304:-78.5
transmembrane serine protease 7ENSG00000176040TMPRSS7chr3:112034843-112081269:+67.5
adenylate cyclase 5ENSG00000173175ADCY5chr3:123282296-123449758:-78.5
claudin 18ENSG00000066405CLDN18chr3:137998735-138033655:+78.5
5-hydroxytryptamine receptor 3DENSG00000186090HTR3Dchr3:184031544-184039369:+78.5
5-hydroxytryptamine receptor 3CENSG00000178084HTR3Cchr3:184053047-184060671:+78.5
5-hydroxytryptamine receptor 3EENSG00000186038HTR3Echr3:184097064-184106995:+78.5
leucine rich repeat containing 15ENSG00000172061LRRC15chr3:194355247-194369743:-610.5
solute carrier family 26 member 1ENSG00000145217SLC26A1chr4:979073-993440:-79.5
solute carrier family 34 member 2ENSG00000157765SLC34A2chr4:25655301-25678748:+79.5
glutamate ionotropic receptor delta type subunit 2ENSG00000152208GRID2chr4:92303622-93774556:+79.5
tetraspanin 5ENSG00000168785TSPAN5chr4:98470367-98658629:-79.5
transmembrane protein 154ENSG00000170006TMEM154chr4:152618632-152680165:-68.5
acid sensing ion channel subunit family member 5ENSG00000256394ASIC5chr4:155829729-155866273:-67.5
glycoprotein M6AENSG00000150625GPM6Achr4:175632934-176002664:-79.5
claudin 22ENSG00000177300CLDN22chr4:183318194-183320774:-78.5
MARVEL domain containing 2ENSG00000152939MARVELD2chr5:69415112-69444330:+79.5

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