GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
modulator of VRAC current 1 | ENSG00000100427 | MLC1 | chr22:50059391-50085902:- | 6 | 7.5 |
caveolin 3 | ENSG00000182533 | CAV3 | chr3:8733800-8841808:+ | 7 | 8.5 |
solute carrier family 22 member 13 | ENSG00000172940 | SLC22A13 | chr3:38265812-38278315:+ | 6 | 7.5 |
gamma-aminobutyric acid type A receptor subunit rho3 (gene/pseudogene) | ENSG00000183185 | GABRR3 | chr3:97986673-98035304:- | 7 | 8.5 |
transmembrane serine protease 7 | ENSG00000176040 | TMPRSS7 | chr3:112034843-112081269:+ | 6 | 7.5 |
adenylate cyclase 5 | ENSG00000173175 | ADCY5 | chr3:123282296-123449758:- | 7 | 8.5 |
claudin 18 | ENSG00000066405 | CLDN18 | chr3:137998735-138033655:+ | 7 | 8.5 |
5-hydroxytryptamine receptor 3D | ENSG00000186090 | HTR3D | chr3:184031544-184039369:+ | 7 | 8.5 |
5-hydroxytryptamine receptor 3C | ENSG00000178084 | HTR3C | chr3:184053047-184060671:+ | 7 | 8.5 |
5-hydroxytryptamine receptor 3E | ENSG00000186038 | HTR3E | chr3:184097064-184106995:+ | 7 | 8.5 |
leucine rich repeat containing 15 | ENSG00000172061 | LRRC15 | chr3:194355247-194369743:- | 6 | 10.5 |
solute carrier family 26 member 1 | ENSG00000145217 | SLC26A1 | chr4:979073-993440:- | 7 | 9.5 |
solute carrier family 34 member 2 | ENSG00000157765 | SLC34A2 | chr4:25655301-25678748:+ | 7 | 9.5 |
glutamate ionotropic receptor delta type subunit 2 | ENSG00000152208 | GRID2 | chr4:92303622-93774556:+ | 7 | 9.5 |
tetraspanin 5 | ENSG00000168785 | TSPAN5 | chr4:98470367-98658629:- | 7 | 9.5 |
transmembrane protein 154 | ENSG00000170006 | TMEM154 | chr4:152618632-152680165:- | 6 | 8.5 |
acid sensing ion channel subunit family member 5 | ENSG00000256394 | ASIC5 | chr4:155829729-155866273:- | 6 | 7.5 |
glycoprotein M6A | ENSG00000150625 | GPM6A | chr4:175632934-176002664:- | 7 | 9.5 |
claudin 22 | ENSG00000177300 | CLDN22 | chr4:183318194-183320774:- | 7 | 8.5 |
MARVEL domain containing 2 | ENSG00000152939 | MARVELD2 | chr5:69415112-69444330:+ | 7 | 9.5 |
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