GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
polycystin 1 like 3, transient receptor potential channel interactingENSG00000277481PKD1L3chr16:71929538-71999978:-67.5
solute carrier family 13 member 5ENSG00000141485SLC13A5chr17:6684713-6713567:-67.5
solute carrier family 47 member 1ENSG00000142494SLC47A1chr17:19495385-19579034:+67.5
gap junction protein gamma 1ENSG00000182963GJC1chr17:44798448-44830816:-79.5
calcium voltage-gated channel auxiliary subunit gamma 1ENSG00000108878CACNG1chr17:67044590-67056797:+67.5
CD300 molecule like family member bENSG00000178789CD300LBchr17:74521174-74531474:-67.5
zinc activated ion channelENSG00000186919ZACNchr17:76071961-76083666:+78.5
glutamate ionotropic receptor NMDA type subunit 3BENSG00000116032GRIN3Bchr19:1000419-1009732:+78.5
transmembrane serine protease 9ENSG00000178297TMPRSS9chr19:2389771-2426239:+67.5
tweety family member 1ENSG00000167614TTYH1chr19:54415219-54436900:+78.5
leukocyte immunoglobulin like receptor A2ENSG00000239998LILRA2chr19:54572920-54590287:+67
leukocyte immunoglobulin like receptor B4ENSG00000186818LILRB4chr19:54643889-54670359:+610.5
major facilitator superfamily domain containing 2BENSG00000205639MFSD2Bchr2:24010081-24063321:+78.5
vesicle associated membrane protein 5ENSG00000168899VAMP5chr2:85584408-85593412:+711.5
solute carrier family 11 member 1ENSG00000018280SLC11A1chr2:218382029-218396894:+78.5
ATP binding cassette subfamily B member 6 (Langereis blood group)ENSG00000115657ABCB6chr2:219209768-219218990:-611.5
transmembrane 4 L six family member 20ENSG00000168955TM4SF20chr2:227362156-227381995:-67.5
leucine rich repeat neuronal 4ENSG00000125872LRRN4chr20:6040778-6054049:-67.5
claudin 8ENSG00000156284CLDN8chr21:30214006-30216073:-78.5
extracellular leucine rich repeat and fibronectin type III domain containing 2ENSG00000166897ELFN2chr22:37367960-37427470:-69.5

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