GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
solute carrier organic anion transporter family member 1B7 (putative)ENSG00000205754SLCO1B7chr12:21015696-21092745:+78.5
sarcospanENSG00000123096SSPNchr12:26121991-26299290:+68.5
Fas apoptotic inhibitory molecule 2ENSG00000135472FAIM2chr12:49866896-49904217:-67.5
solute carrier family 5 member 8ENSG00000256870SLC5A8chr12:101155493-101210407:-67.5
transmembrane protein 119ENSG00000183160TMEM119chr12:108589846-108598320:-68.5
purinergic receptor P2X 2ENSG00000187848P2RX2chr12:132618780-132622386:+78.5
gap junction protein alpha 3ENSG00000121743GJA3chr13:20138255-20161049:-78.5
solute carrier family 46 member 3ENSG00000139508SLC46A3chr13:28700064-28718970:-67.5
SLIT and NTRK like family member 5ENSG00000165300SLITRK5chr13:87672615-87696272:+710.5
solute carrier family 15 member 1ENSG00000088386SLC15A1chr13:98683801-98752654:-78.5
solute carrier family 24 member 4ENSG00000140090SLC24A4chr14:92322581-92501483:+78.5
dispatched RND transporter family member 2ENSG00000140323DISP2chr15:40358235-40378639:+68
transmembrane protein 204ENSG00000131634TMEM204chr16:1528688-1555580:+67.5
ATP binding cassette subfamily A member 3ENSG00000167972ABCA3chr16:2275881-2340746:-68.5
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidaseENSG00000103174NAGPAchr16:5024844-5034141:-69.5
epithelial membrane protein 2ENSG00000213853EMP2chr16:10528422-10580698:-79.5
calcium voltage-gated channel auxiliary subunit gamma 3ENSG00000006116CACNG3chr16:24255553-24362801:+78.5
syntaxin 4ENSG00000103496STX4chr16:31032889-31042975:+712.5
matrix metallopeptidase 15ENSG00000102996MMP15chr16:58025566-58046901:+68.5
dipeptidase 2ENSG00000167261DPEP2chr16:67987394-68000586:-68.5

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