GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
potassium two pore domain channel subfamily K member 2 | ENSG00000082482 | KCNK2 | chr1:215005775-215237093:+ | 7 | 10.5 |
interleukin 15 receptor subunit alpha | ENSG00000134470 | IL15RA | chr10:5937569-5978187:- | 6 | 8.5 |
plexin domain containing 2 | ENSG00000120594 | PLXDC2 | chr10:19816239-20289856:+ | 6 | 11.5 |
collagen type XVII alpha 1 chain | ENSG00000065618 | COL17A1 | chr10:104031286-104086002:- | 6 | 9.5 |
interferon induced transmembrane protein 3 | ENSG00000142089 | IFITM3 | chr11:319669-327537:- | 7 | 12.5 |
solute carrier family 22 member 18 | ENSG00000110628 | SLC22A18 | chr11:2899721-2925246:+ | 6 | 7.5 |
solute carrier family 5 member 12 | ENSG00000148942 | SLC5A12 | chr11:26667019-26723427:- | 6 | 7.5 |
KIAA1549 like | ENSG00000110427 | KIAA1549L | chr11:33542072-33674102:+ | 6 | 9.5 |
solute carrier family 1 member 2 | ENSG00000110436 | SLC1A2 | chr11:35251206-35420063:- | 6 | 8.5 |
CD248 molecule | ENSG00000174807 | CD248 | chr11:66314487-66317044:- | 7 | 11.5 |
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 | ENSG00000110719 | TCIRG1 | chr11:68039016-68050895:+ | 7 | 11.5 |
NADPH oxidase 4 | ENSG00000086991 | NOX4 | chr11:89324356-89498187:- | 7 | 8.5 |
layilin | ENSG00000204381 | LAYN | chr11:111540280-111561745:+ | 6 | 8.5 |
DS cell adhesion molecule like 1 | ENSG00000177103 | DSCAML1 | chr11:117427773-117817525:- | 7 | 8.5 |
solute carrier family 2 member 14 | ENSG00000173262 | SLC2A14 | chr12:7812512-7891148:- | 6 | 12 |
C-type lectin domain family 4 member A | ENSG00000111729 | CLEC4A | chr12:8123632-8138607:+ | 6 | 8.5 |
killer cell lectin like receptor D1 | ENSG00000134539 | KLRD1 | chr12:10226058-10329600:+ | 6 | 7.5 |
MANSC domain containing 1 | ENSG00000111261 | MANSC1 | chr12:12326056-12350541:- | 6 | 8.5 |
ADP-ribosyltransferase 4 (Dombrock blood group) | ENSG00000111339 | ART4 | chr12:14825569-14843495:- | 6 | 7.5 |
solute carrier organic anion transporter family member 1C1 | ENSG00000139155 | SLCO1C1 | chr12:20695355-20753386:+ | 7 | 8.5 |
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