GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
potassium two pore domain channel subfamily K member 2ENSG00000082482KCNK2chr1:215005775-215237093:+710.5
interleukin 15 receptor subunit alphaENSG00000134470IL15RAchr10:5937569-5978187:-68.5
plexin domain containing 2ENSG00000120594PLXDC2chr10:19816239-20289856:+611.5
collagen type XVII alpha 1 chainENSG00000065618COL17A1chr10:104031286-104086002:-69.5
interferon induced transmembrane protein 3ENSG00000142089IFITM3chr11:319669-327537:-712.5
solute carrier family 22 member 18ENSG00000110628SLC22A18chr11:2899721-2925246:+67.5
solute carrier family 5 member 12ENSG00000148942SLC5A12chr11:26667019-26723427:-67.5
KIAA1549 likeENSG00000110427KIAA1549Lchr11:33542072-33674102:+69.5
solute carrier family 1 member 2ENSG00000110436SLC1A2chr11:35251206-35420063:-68.5
CD248 moleculeENSG00000174807CD248chr11:66314487-66317044:-711.5
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3ENSG00000110719TCIRG1chr11:68039016-68050895:+711.5
NADPH oxidase 4ENSG00000086991NOX4chr11:89324356-89498187:-78.5
layilinENSG00000204381LAYNchr11:111540280-111561745:+68.5
DS cell adhesion molecule like 1ENSG00000177103DSCAML1chr11:117427773-117817525:-78.5
solute carrier family 2 member 14ENSG00000173262SLC2A14chr12:7812512-7891148:-612
C-type lectin domain family 4 member AENSG00000111729CLEC4Achr12:8123632-8138607:+68.5
killer cell lectin like receptor D1ENSG00000134539KLRD1chr12:10226058-10329600:+67.5
MANSC domain containing 1ENSG00000111261MANSC1chr12:12326056-12350541:-68.5
ADP-ribosyltransferase 4 (Dombrock blood group)ENSG00000111339ART4chr12:14825569-14843495:-67.5
solute carrier organic anion transporter family member 1C1ENSG00000139155SLCO1C1chr12:20695355-20753386:+78.5

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