GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
potassium voltage-gated channel modifier subfamily V member 2ENSG00000168263KCNV2chr9:2717502-2730037:+78.5
IZUMO family member 3ENSG00000205442IZUMO3chr9:24542952-24545946:-67.5
carbonic anhydrase 9ENSG00000107159CA9chr9:35673856-35681159:+69.5
contactin associated protein family member 3ENSG00000106714CNTNAP3chr9:39072767-39288315:-68.5
sushi domain containing 3ENSG00000157303SUSD3chr9:93058688-93085138:+68.5
muscle associated receptor tyrosine kinaseENSG00000030304MUSKchr9:110668771-110801579:+79.5
collectrin, amino acid transport regulatorENSG00000147003TMEM27chrX:15627318-15665031:-67.5
phosphate regulating endopeptidase homolog X-linkedENSG00000102174PHEXchrX:22032441-22251310:+67.5
gamma-aminobutyric acid type A receptor subunit thetaENSG00000268089GABRQchrX:152638183-152657534:+78.5
protocadherin 11 Y-linkedENSG00000099715PCDH11YchrY:5000226-5742224:+79.5
neuroligin 4 Y-linkedENSG00000165246NLGN4YchrY:14522638-14845650:+78.5
CD52 moleculeENSG00000169442CD52chr1:26317957-26320523:+78.5
sodium/potassium transporting ATPase interacting 1ENSG00000084628NKAIN1chr1:31179745-31239554:-67.5
CUB and Sushi multiple domains 2ENSG00000121904CSMD2chr1:33513999-34165842:-67.5
ATP binding cassette subfamily A member 4ENSG00000198691ABCA4chr1:93992835-94121132:-67.5
leucine rich repeats and immunoglobulin like domains 2ENSG00000198799LRIG2chr1:113073209-113132260:+68.5
synaptotagmin 6ENSG00000134207SYT6chr1:114089291-114153919:-78.5
Fc receptor like 1ENSG00000163534FCRL1chr1:157794403-157820105:-69.5
SUN domain containing ossification factorENSG00000094975SUCOchr1:172532349-172611833:+67.5
calcium voltage-gated channel subunit alpha1 SENSG00000081248CACNA1Schr1:201039512-201112566:-67.5

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