GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
protocadherin beta 14ENSG00000120327PCDHB14chr5:141222932-141227759:+78.5
protocadherin beta 15ENSG00000113248PCDHB15chr5:141245349-141249365:+78.5
protocadherin 12ENSG00000113555PCDH12chr5:141943585-141969741:-78.5
discoidin domain receptor tyrosine kinase 1ENSG00000204580DDR1chr6:30876421-30900156:+68.5
mucin 21, cell surface associatedENSG00000204544MUC21chr6:30983718-30989903:+78.5
major histocompatibility complex, class II, DO alphaENSG00000204252HLA-DOAchr6:33004178-33009612:-67.5
triggering receptor expressed on myeloid cells like 2ENSG00000112195TREML2chr6:41190277-41201194:-69.5
triggering receptor expressed on myeloid cells 1ENSG00000124731TREM1chr6:41267926-41286719:-67.5
natural cytotoxicity triggering receptor 2ENSG00000096264NCR2chr6:41335655-41350887:+67.5
GDNF family receptor alpha likeENSG00000187871GFRALchr6:55327469-55402493:+78.5
gamma-aminobutyric acid type A receptor subunit rho1ENSG00000146276GABRR1chr6:89177501-89231278:-78.5
gamma-aminobutyric acid type A receptor subunit rho2ENSG00000111886GABRR2chr6:89257208-89315299:-78.5
EPH receptor A7ENSG00000135333EPHA7chr6:93240020-93419547:-710.5
iodotyrosine deiodinaseENSG00000009765IYDchr6:150368892-150405969:+68
ATP binding cassette subfamily B member 5ENSG00000004846ABCB5chr7:20615207-20777038:+67.5
paired immunoglobin like type 2 receptor betaENSG00000121716PILRBchr7:100352176-100367733:+67.5
sperm adhesion molecule 1ENSG00000106304SPAM1chr7:123925237-123971414:+67.5
cholinergic receptor nicotinic alpha 2 subunitENSG00000120903CHRNA2chr8:27459762-27479883:-78.5
cholinergic receptor nicotinic alpha 6 subunitENSG00000147434CHRNA6chr8:42752620-42796392:-78.5
matrix metallopeptidase 16ENSG00000156103MMP16chr8:88032009-88328025:-78.5

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