GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
solute carrier family 3 member 1ENSG00000138079SLC3A1chr2:44275458-44321494:+67.5
dysferlinENSG00000135636DYSFchr2:71453722-71686768:+612
leucine rich repeat transmembrane neuronal 4ENSG00000176204LRRTM4chr2:76747719-77593319:-67.5
TraB domain containing 2AENSG00000186854TRABD2Achr2:84821650-84907008:-78
inducible T cell costimulatorENSG00000163600ICOSchr2:203936748-203961577:+67.5
ADAM metallopeptidase domain 23ENSG00000114948ADAM23chr2:206443539-206621130:+68.5
cholinergic receptor nicotinic gamma subunitENSG00000196811CHRNGchr2:232539727-232546403:+78.5
protein tyrosine phosphatase receptor type TENSG00000196090PTPRTchr20:42072752-43189970:-67.5
cadherin 22ENSG00000149654CDH22chr20:46173733-46308498:-67.5
interferon gamma receptor 2ENSG00000159128IFNGR2chr21:33402896-33479348:+78.5
DS cell adhesion moleculeENSG00000171587DSCAMchr21:40010999-40847139:-78.5
kringle containing transmembrane protein 1ENSG00000183762KREMEN1chr22:29073078-29168333:+67.5
solute carrier family 16 member 8ENSG00000100156SLC16A8chr22:38078134-38084093:-78.5
interleukin 17 receptor CENSG00000163702IL17RCchr3:9917074-9933630:+67.5
sodium voltage-gated channel alpha subunit 5ENSG00000183873SCN5Achr3:38548057-38649673:-79
EvC ciliary complex subunit 2ENSG00000173040EVC2chr4:5542772-5709548:-68.5
toll like receptor 6ENSG00000174130TLR6chr4:38823715-38856817:-710.5
transmembrane serine protease 11BENSG00000185873TMPRSS11Bchr4:68226653-68245720:-67.5
transmembrane serine protease 11EENSG00000087128TMPRSS11Echr4:68447449-68497604:+67.5
protocadherin 10ENSG00000138650PCDH10chr4:133149315-133208606:+710.5

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