GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
sarcoglycan alphaENSG00000108823SGCAchr17:50164214-50175931:+78.5
solute carrier family 16 member 6ENSG00000108932SLC16A6chr17:68267026-68291267:-67.5
CD300a moleculeENSG00000167851CD300Achr17:74466416-74484796:+69.5
CD300c moleculeENSG00000167850CD300Cchr17:74541108-74546143:-68.5
CD300 molecule like family member fENSG00000186074CD300LFchr17:74694311-74712978:-69.5
glutamate ionotropic receptor NMDA type subunit 2CENSG00000161509GRIN2Cchr17:74842023-74861504:-78.5
secreted and transmembrane 1ENSG00000141574SECTM1chr17:82321024-82334074:-68.5
desmoglein 4ENSG00000175065DSG4chr18:31376777-31414912:+78.5
solute carrier family 14 member 2ENSG00000132874SLC14A2chr18:45212995-45683686:+67.5
neuropilin and tolloid like 1ENSG00000166342NETO1chr18:72742314-72868146:-67.5
C-type lectin domain family 4 member MENSG00000104938CLEC4Mchr19:7763149-7769605:+67.5
solute carrier family 7 member 9ENSG00000021488SLC7A9chr19:32830509-32869766:-68.5
kirre like nephrin family adhesion molecule 2ENSG00000126259KIRREL2chr19:35855861-35867109:+68.5
leucine rich repeat and fibronectin type III domain containing 3ENSG00000126243LRFN3chr19:35935358-35945767:+67.5
glutamate ionotropic receptor NMDA type subunit 2DENSG00000105464GRIN2Dchr19:48394875-48444931:+78.5
calcium voltage-gated channel auxiliary subunit gamma 7ENSG00000105605CACNG7chr19:53909335-53943941:+67.5
T cell-interacting, activating receptor on myeloid cells 1ENSG00000248385TARM1chr19:54069895-54081365:-67.5
leukocyte immunoglobulin like receptor B2ENSG00000131042LILRB2chr19:54238904-54281184:-610.5
protein tyrosine phosphatase receptor type HENSG00000080031PTPRHchr19:55181248-55209506:-67.5
phospholipase B1ENSG00000163803PLB1chr2:28457145-28643788:+78.5

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