GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
delta like canonical Notch ligand 4 | ENSG00000128917 | DLL4 | chr15:40929340-40939072:+ | 6 | 7.5 |
dual oxidase 1 | ENSG00000137857 | DUOX1 | chr15:45129933-45165576:+ | 7 | 8.5 |
protogenin | ENSG00000166450 | PRTG | chr15:55611546-55743090:- | 6 | 8 |
multiple EGF like domains 11 | ENSG00000157890 | MEGF11 | chr15:65895079-66253747:- | 6 | 7.5 |
signaling receptor and transporter of retinol STRA6 | ENSG00000137868 | STRA6 | chr15:74179466-74212267:- | 7 | 10 |
neuregulin 4 | ENSG00000169752 | NRG4 | chr15:75935969-76059795:- | 6 | 7.5 |
cholinergic receptor nicotinic beta 4 subunit | ENSG00000117971 | CHRNB4 | chr15:78624119-78727754:- | 7 | 8.5 |
furin, paired basic amino acid cleaving enzyme | ENSG00000140564 | FURIN | chr15:90868592-90883458:+ | 7 | 10.5 |
claudin 6 | ENSG00000184697 | CLDN6 | chr16:3014712-3020071:- | 7 | 10.5 |
shisa family member 9 | ENSG00000237515 | SHISA9 | chr16:12901620-13240413:+ | 7 | 8.5 |
uromodulin | ENSG00000169344 | UMOD | chr16:20333052-20356301:- | 6 | 7.5 |
zona pellucida glycoprotein 2 | ENSG00000103310 | ZP2 | chr16:21197450-21214510:- | 6 | 7.5 |
transmembrane protein 219 | ENSG00000149932 | TMEM219 | chr16:29940885-29973052:+ | 6 | 8.5 |
integrin subunit alpha D | ENSG00000156886 | ITGAD | chr16:31393312-31426505:+ | 6 | 7.5 |
cadherin 16 | ENSG00000166589 | CDH16 | chr16:66908122-66918984:- | 7 | 8.5 |
transient receptor potential cation channel subfamily V member 3 | ENSG00000167723 | TRPV3 | chr17:3510502-3557995:- | 7 | 11.5 |
asialoglycoprotein receptor 2 | ENSG00000161944 | ASGR2 | chr17:7101322-7115700:- | 6 | 7.5 |
transmembrane and immunoglobulin domain containing 1 | ENSG00000182271 | TMIGD1 | chr17:30316333-30334059:- | 6 | 7.5 |
receptor activity modifying protein 2 | ENSG00000131477 | RAMP2 | chr17:42758447-42763041:+ | 7 | 8.5 |
CD300 molecule like family member g | ENSG00000161649 | CD300LG | chr17:43847148-43863629:+ | 6 | 7.5 |
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