GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
delta like canonical Notch ligand 4ENSG00000128917DLL4chr15:40929340-40939072:+67.5
dual oxidase 1ENSG00000137857DUOX1chr15:45129933-45165576:+78.5
protogeninENSG00000166450PRTGchr15:55611546-55743090:-68
multiple EGF like domains 11ENSG00000157890MEGF11chr15:65895079-66253747:-67.5
signaling receptor and transporter of retinol STRA6ENSG00000137868STRA6chr15:74179466-74212267:-710
neuregulin 4ENSG00000169752NRG4chr15:75935969-76059795:-67.5
cholinergic receptor nicotinic beta 4 subunitENSG00000117971CHRNB4chr15:78624119-78727754:-78.5
furin, paired basic amino acid cleaving enzymeENSG00000140564FURINchr15:90868592-90883458:+710.5
claudin 6ENSG00000184697CLDN6chr16:3014712-3020071:-710.5
shisa family member 9ENSG00000237515SHISA9chr16:12901620-13240413:+78.5
uromodulinENSG00000169344UMODchr16:20333052-20356301:-67.5
zona pellucida glycoprotein 2ENSG00000103310ZP2chr16:21197450-21214510:-67.5
transmembrane protein 219ENSG00000149932TMEM219chr16:29940885-29973052:+68.5
integrin subunit alpha DENSG00000156886ITGADchr16:31393312-31426505:+67.5
cadherin 16ENSG00000166589CDH16chr16:66908122-66918984:-78.5
transient receptor potential cation channel subfamily V member 3ENSG00000167723TRPV3chr17:3510502-3557995:-711.5
asialoglycoprotein receptor 2ENSG00000161944ASGR2chr17:7101322-7115700:-67.5
transmembrane and immunoglobulin domain containing 1ENSG00000182271TMIGD1chr17:30316333-30334059:-67.5
receptor activity modifying protein 2ENSG00000131477RAMP2chr17:42758447-42763041:+78.5
CD300 molecule like family member gENSG00000161649CD300LGchr17:43847148-43863629:+67.5

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