GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
bestrophin 1ENSG00000167995BEST1chr11:61949821-61965515:+68
potassium two pore domain channel subfamily K member 4ENSG00000182450KCNK4chr11:64291302-64300031:+710.5
RELT TNF receptorENSG00000054967RELTchr11:73376264-73397474:+67.5
solute carrier organic anion transporter family member 2B1ENSG00000137491SLCO2B1chr11:75100563-75206549:+79.5
transmembrane protein 123ENSG00000152558TMEM123chr11:102396332-102470384:-69.5
uroplakin 2ENSG00000110375UPK2chr11:118925164-118958559:+67.5
GRAM domain containing 1BENSG00000023171GRAMD1Bchr11:123454398-123627774:+67.5
kirre like nephrin family adhesion molecule 3ENSG00000149571KIRREL3chr11:126423359-127003460:-67.5
solute carrier family 6 member 13ENSG00000010379SLC6A13chr12:220621-262873:-78.5
lymphocyte activating 3ENSG00000089692LAG3chr12:6772512-6778455:+68.5
C-type lectin domain family 12 member BENSG00000256660CLEC12Bchr12:10010627-10018619:+67.5
C-type lectin domain containing 7AENSG00000172243CLEC7Achr12:10116777-10130258:-67.5
taste 2 receptor member 14ENSG00000212127TAS2R14chr12:10937406-11171573:-68
protein tyrosine phosphatase receptor type OENSG00000151490PTPROchr12:15322397-15597399:+67.5
solute carrier family 38 member 2ENSG00000134294SLC38A2chr12:46358189-46372867:-712.5
activin A receptor type 1BENSG00000135503ACVR1Bchr12:51951667-51997078:+79.5
klothoENSG00000133116KLchr13:33016433-33066145:+67.5
claudin 10ENSG00000134873CLDN10chr13:95433604-95579759:+78.5
solute carrier family 39 member 2ENSG00000165794SLC39A2chr14:20999255-21001871:+78.5
FLVCR heme transporter 2ENSG00000119686FLVCR2chr14:75578617-75663214:+67.5

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