GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
bestrophin 1 | ENSG00000167995 | BEST1 | chr11:61949821-61965515:+ | 6 | 8 |
potassium two pore domain channel subfamily K member 4 | ENSG00000182450 | KCNK4 | chr11:64291302-64300031:+ | 7 | 10.5 |
RELT TNF receptor | ENSG00000054967 | RELT | chr11:73376264-73397474:+ | 6 | 7.5 |
solute carrier organic anion transporter family member 2B1 | ENSG00000137491 | SLCO2B1 | chr11:75100563-75206549:+ | 7 | 9.5 |
transmembrane protein 123 | ENSG00000152558 | TMEM123 | chr11:102396332-102470384:- | 6 | 9.5 |
uroplakin 2 | ENSG00000110375 | UPK2 | chr11:118925164-118958559:+ | 6 | 7.5 |
GRAM domain containing 1B | ENSG00000023171 | GRAMD1B | chr11:123454398-123627774:+ | 6 | 7.5 |
kirre like nephrin family adhesion molecule 3 | ENSG00000149571 | KIRREL3 | chr11:126423359-127003460:- | 6 | 7.5 |
solute carrier family 6 member 13 | ENSG00000010379 | SLC6A13 | chr12:220621-262873:- | 7 | 8.5 |
lymphocyte activating 3 | ENSG00000089692 | LAG3 | chr12:6772512-6778455:+ | 6 | 8.5 |
C-type lectin domain family 12 member B | ENSG00000256660 | CLEC12B | chr12:10010627-10018619:+ | 6 | 7.5 |
C-type lectin domain containing 7A | ENSG00000172243 | CLEC7A | chr12:10116777-10130258:- | 6 | 7.5 |
taste 2 receptor member 14 | ENSG00000212127 | TAS2R14 | chr12:10937406-11171573:- | 6 | 8 |
protein tyrosine phosphatase receptor type O | ENSG00000151490 | PTPRO | chr12:15322397-15597399:+ | 6 | 7.5 |
solute carrier family 38 member 2 | ENSG00000134294 | SLC38A2 | chr12:46358189-46372867:- | 7 | 12.5 |
activin A receptor type 1B | ENSG00000135503 | ACVR1B | chr12:51951667-51997078:+ | 7 | 9.5 |
klotho | ENSG00000133116 | KL | chr13:33016433-33066145:+ | 6 | 7.5 |
claudin 10 | ENSG00000134873 | CLDN10 | chr13:95433604-95579759:+ | 7 | 8.5 |
solute carrier family 39 member 2 | ENSG00000165794 | SLC39A2 | chr14:20999255-21001871:+ | 7 | 8.5 |
FLVCR heme transporter 2 | ENSG00000119686 | FLVCR2 | chr14:75578617-75663214:+ | 6 | 7.5 |
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