GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
transient receptor potential cation channel subfamily A member 1 | ENSG00000104321 | TRPA1 | chr8:72019917-72075617:- | 6 | 10.5 |
leucine rich repeat containing 8 VRAC subunit A | ENSG00000136802 | LRRC8A | chr9:128882112-128918039:+ | 6 | 14.5 |
calsyntenin 1 | ENSG00000171603 | CLSTN1 | chr1:9729026-9824526:- | 7 | 11.5 |
chloride voltage-gated channel Kb | ENSG00000184908 | CLCNKB | chr1:16043736-16057308:+ | 7 | 8.5 |
non-compact myelin associated protein | ENSG00000184454 | NCMAP | chr1:24556111-24609328:+ | 6 | 7.5 |
EPH receptor A10 | ENSG00000183317 | EPHA10 | chr1:37713880-37765133:- | 7 | 8.5 |
rhomboid like 2 | ENSG00000158315 | RHBDL2 | chr1:38885807-38941799:- | 6 | 7.5 |
claudin 19 | ENSG00000164007 | CLDN19 | chr1:42733093-42740254:- | 7 | 8.5 |
Fc receptor like 4 | ENSG00000163518 | FCRL4 | chr1:157573749-157598080:- | 6 | 7.5 |
CD1e molecule | ENSG00000158488 | CD1E | chr1:158353696-158357553:+ | 7 | 8.5 |
Fas ligand | ENSG00000117560 | FASLG | chr1:172659018-172666874:+ | 6 | 7.5 |
usherin | ENSG00000042781 | USH2A | chr1:215622894-216423396:- | 6 | 7.5 |
leucine rich repeat transmembrane neuronal 3 | ENSG00000198739 | LRRTM3 | chr10:66926006-67099830:+ | 6 | 7.5 |
cadherin related 23 | ENSG00000107736 | CDH23 | chr10:71396934-71815947:+ | 7 | 9.5 |
bone morphogenetic protein receptor type 1A | ENSG00000107779 | BMPR1A | chr10:86756650-86932838:+ | 7 | 10.5 |
zinc finger FYVE-type containing 27 | ENSG00000155256 | ZFYVE27 | chr10:97737121-97760907:+ | 7 | 9.5 |
olfactory receptor family 51 subfamily B member 5 | ENSG00000242180 | OR51B5 | chr11:5342586-5343524:- | 7 | 8.5 |
solute carrier family 6 member 5 | ENSG00000165970 | SLC6A5 | chr11:20599400-20659285:+ | 7 | 8.5 |
mucin 15, cell surface associated | ENSG00000169550 | MUC15 | chr11:26559033-26572233:- | 6 | 7.5 |
zona pellucida glycoprotein 1 | ENSG00000149506 | ZP1 | chr11:60867562-60875693:+ | 6 | 7.5 |
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