GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
transient receptor potential cation channel subfamily A member 1ENSG00000104321TRPA1chr8:72019917-72075617:-610.5
leucine rich repeat containing 8 VRAC subunit AENSG00000136802LRRC8Achr9:128882112-128918039:+614.5
calsyntenin 1ENSG00000171603CLSTN1chr1:9729026-9824526:-711.5
chloride voltage-gated channel KbENSG00000184908CLCNKBchr1:16043736-16057308:+78.5
non-compact myelin associated proteinENSG00000184454NCMAPchr1:24556111-24609328:+67.5
EPH receptor A10ENSG00000183317EPHA10chr1:37713880-37765133:-78.5
rhomboid like 2ENSG00000158315RHBDL2chr1:38885807-38941799:-67.5
claudin 19ENSG00000164007CLDN19chr1:42733093-42740254:-78.5
Fc receptor like 4ENSG00000163518FCRL4chr1:157573749-157598080:-67.5
CD1e moleculeENSG00000158488CD1Echr1:158353696-158357553:+78.5
Fas ligandENSG00000117560FASLGchr1:172659018-172666874:+67.5
usherinENSG00000042781USH2Achr1:215622894-216423396:-67.5
leucine rich repeat transmembrane neuronal 3ENSG00000198739LRRTM3chr10:66926006-67099830:+67.5
cadherin related 23ENSG00000107736CDH23chr10:71396934-71815947:+79.5
bone morphogenetic protein receptor type 1AENSG00000107779BMPR1Achr10:86756650-86932838:+710.5
zinc finger FYVE-type containing 27ENSG00000155256ZFYVE27chr10:97737121-97760907:+79.5
olfactory receptor family 51 subfamily B member 5ENSG00000242180OR51B5chr11:5342586-5343524:-78.5
solute carrier family 6 member 5ENSG00000165970SLC6A5chr11:20599400-20659285:+78.5
mucin 15, cell surface associatedENSG00000169550MUC15chr11:26559033-26572233:-67.5
zona pellucida glycoprotein 1ENSG00000149506ZP1chr11:60867562-60875693:+67.5

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