colony stimulating factor 2 receptor beta common subunit
Location:
22q12.3
Also known as:
IL3RB, CD131, IL5RB, betaGMR
Entrez ID:
1439
Ensembl ID:
ENSG00000100368
Summary:
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]
Overall distribution
Tissue specific distribution
Overall distribution
Tissue specific distribution
Gscore (Amp):
0.00
Gscore (Del):
0.00
Overall distribution
Tissue specific distribution
Mscore:
0.00
Overall
Tissue specific
Total fusion occurrence:
0
Overall
Tissue specific
STRONGLY SELECTIVE
Functional class:
Not specified
JensenLab PubMed score:
24.85 (Percentile rank: 51.03%)
PubTator score:
123.98 (Percentile rank: 80.49%)
Target development/druggability level:
TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action.
Tractability (small molecule):
Predicted TractableTargets with a predicted Ro5 druggable domain (druggable genome); Targets with a drugEBIlity score equal or greater than 0
Tractability (antibody):
Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets
