GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
prostate androgen-regulated mucin-like protein 1ENSG00000169116PARM1chr4:74933095-75050115:+1213.5
glutamyl aminopeptidaseENSG00000138792ENPEPchr4:110365733-110565285:+1213.5
cadherin 6ENSG00000113361CDH6chr5:31193750-31329146:+1318.5
LIF receptor subunit alphaENSG00000113594LIFRchr5:38474963-38608354:-1315.5
phospholipid phosphatase 1ENSG00000067113PPAP2Achr5:55424854-55535050:-1318
CD180 moleculeENSG00000134061CD180chr5:67179613-67196799:-1216.5
platelet derived growth factor receptor betaENSG00000113721PDGFRBchr5:150113837-150155872:-1318.5
butyrophilin subfamily 3 member A3ENSG00000111801BTN3A3chr6:26440472-26453415:+1316.5
TNF receptor superfamily member 21ENSG00000146072TNFRSF21chr6:47231532-47309905:-1316.5
ectonucleotide pyrophosphatase/phosphodiesterase 1ENSG00000197594ENPP1chr6:131808016-131895155:+1319.5
integrin subunit beta 8ENSG00000105855ITGB8chr7:20330702-20415754:+1315.5
neuronal cell adhesion moleculeENSG00000091129NRCAMchr7:108147623-108456717:-1216.5
cadherin 17ENSG00000079112CDH17chr8:94127171-94217303:-1315.5
CD274 moleculeENSG00000120217CD274chr9:5450503-5470566:+1317.5
neurotrophic receptor tyrosine kinase 2ENSG00000148053NTRK2chr9:84668551-85027070:+1316.5
semaphorin 4DENSG00000187764SEMA4Dchr9:89360787-89498130:-1320.5
colony stimulating factor 2 receptor subunit alphaENSG00000198223CSF2RAchrX:1268800-1310381:+1318.5
vascular cell adhesion molecule 1ENSG00000162692VCAM1chr1:100719742-100739045:+1317.5
notch receptor 2ENSG00000134250NOTCH2chr1:119911553-120069626:-1218.5
myelin protein zero like 1ENSG00000197965MPZL1chr1:167721192-167791919:+1220.5

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