GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
purinergic receptor P2Y14ENSG00000174944P2RY14chr3:151212117-151278467:-610
neuropeptide Y receptor Y5ENSG00000164129NPY5Rchr4:163343939-163351934:+69
melatonin receptor 1AENSG00000168412MTNR1Achr4:186533655-186555567:-710
dopamine receptor D1ENSG00000184845DRD1chr5:175440039-175444208:-710
olfactory receptor family 4 subfamily F member 5ENSG00000186092OR4F5chr1:69091-70008:+68
G protein-coupled receptor 153ENSG00000158292GPR153chr1:6247346-6260975:-68
adhesion G protein-coupled receptor B2ENSG00000121753ADGRB2chr1:31727117-31764893:-79
relaxin family peptide/INSL5 receptor 4ENSG00000173080RXFP4chr1:155941710-155942949:+79
olfactory receptor family 10 subfamily T member 2ENSG00000186306OR10T2chr1:158398522-158399466:-68
olfactory receptor family 10 subfamily K member 2ENSG00000180708OR10K2chr1:158419928-158420866:-68
olfactory receptor family 10 subfamily K member 1ENSG00000173285OR10K1chr1:158465562-158466503:+68
olfactory receptor family 10 subfamily R member 2ENSG00000198965OR10R2chr1:158479878-158480885:+68
olfactory receptor family 10 subfamily Z member 1ENSG00000198967OR10Z1chr1:158606439-158607380:+68
olfactory receptor family 6 subfamily N member 1ENSG00000197403OR6N1chr1:158765744-158766682:-68
olfactory receptor family 10 subfamily J member 3ENSG00000196266OR10J3chr1:159313670-159314659:-68
olfactory receptor family 10 subfamily J member 1ENSG00000196184OR10J1chr1:159439722-159440811:+68
olfactory receptor family 10 subfamily J member 5ENSG00000184155OR10J5chr1:159535078-159536007:-79
G protein-coupled receptor 52ENSG00000203737GPR52chr1:174448111-174449198:+79
olfactory receptor family 2 subfamily B member 11ENSG00000177535OR2B11chr1:247451029-247451982:-68
olfactory receptor family 13 subfamily G member 1ENSG00000197437OR13G1chr1:247672118-247673041:-68

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