GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
sulfatase 1ENSG00000137573SULF1chr8:69466624-69660915:+89.5
IgLON family member 5ENSG00000142549IGLON5chr19:51311848-51330354:+78
platelet derived growth factor CENSG00000145431PDGFCchr4:156760454-156971394:-77
adenosine A2a receptorENSG00000128271ADORA2Achr22:24417879-24442360:+712
prostaglandin E receptor 4ENSG00000171522PTGER4chr5:40679498-40693735:+611
calcitonin receptorENSG00000004948CALCRchr7:93424487-93574730:-611
opioid receptor delta 1ENSG00000116329OPRD1chr1:28812142-28871267:+711
hypocretin receptor 1ENSG00000121764HCRTR1chr1:31617686-31632518:+711
cholinergic receptor muscarinic 1ENSG00000168539CHRM1chr11:62908679-62921807:-711
corticotropin releasing hormone receptor 1ENSG00000120088CRHR1chr17:45784280-45835828:+610
free fatty acid receptor 1ENSG00000126266FFAR1chr19:35351552-35353862:+610
opioid related nociceptin receptor 1ENSG00000125510OPRL1chr20:64080173-64100643:+711
C-C motif chemokine receptor 9ENSG00000173585CCR9chr3:45886504-45903177:+713
dopamine receptor D3ENSG00000151577DRD3chr3:114128652-114199407:-711
rhodopsinENSG00000163914RHOchr3:129528640-129535169:+712
purinergic receptor P2Y12ENSG00000169313P2RY12chr3:151337380-151384812:-611
hypocretin receptor 2ENSG00000137252HCRTR2chr6:55106460-55282620:+711
purinergic receptor P2Y2ENSG00000175591P2RY2chr11:73218298-73236352:+69
glutamate metabotropic receptor 5ENSG00000168959GRM5chr11:88504576-89065945:-711
cholinergic receptor nicotinic alpha 7 subunitENSG00000175344CHRNA7chr15:32030488-32172521:+711.5

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