GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
transmembrane protein 200CENSG00000206432TMEM200Cchr18:5882072-5895955:-78.5
CD24 moleculeENSG00000272398CD24chr6:106969831-106975627:-78
KIAA1549ENSG00000122778KIAA1549chr7:138831381-138981318:-712.5
TraB domain containing 2BENSG00000269113TRABD2Bchr1:47760528-47996895:-88.5
netrin G1ENSG00000162631NTNG1chr1:107140007-107483458:+78
sphingomyelin phosphodiesterase 1ENSG00000166311SMPD1chr11:6390431-6394998:+79
reticulon 4 receptor like 2ENSG00000186907RTN4RL2chr11:57460549-57477534:+77.5
reticulon 4 receptor like 1ENSG00000185924RTN4RL1chr17:1934677-2025345:-77
neuraminidase 1ENSG00000204386NEU1chr6:31857659-31862906:-79
paraoxonase 2ENSG00000105854PON2chr7:95404863-95435329:-713
sphingomyelin phosphodiesterase acid like 3BENSG00000130768SMPDL3Bchr1:27934993-27959157:+711.5
voltage dependent anion channel 1ENSG00000213585VDAC1chr5:133971915-134005133:-716
cubilinENSG00000107611CUBNchr10:16823964-17129831:-89
collagen type XXVI alpha 1 chainENSG00000160963COL26A1chr7:101362820-101559024:+710
enolase 1ENSG00000074800ENO1chr1:8861002-8879249:-714
contactin 2ENSG00000184144CNTN2chr1:205043197-205078499:+89
tetratricopeptide repeat domain 17ENSG00000052841TTC17chr11:43358932-43494933:+78
milk fat globule EGF and factor V/VIII domain containingENSG00000140545MFGE8chr15:88898683-88913411:-712
sulfatase 2ENSG00000196562SULF2chr20:47656348-47786616:-88.5
signal peptide, CUB domain and EGF like domain containing 1ENSG00000159307SCUBE1chr22:43197283-43343388:-77

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