GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
transmembrane protein 200C | ENSG00000206432 | TMEM200C | chr18:5882072-5895955:- | 7 | 8.5 |
CD24 molecule | ENSG00000272398 | CD24 | chr6:106969831-106975627:- | 7 | 8 |
KIAA1549 | ENSG00000122778 | KIAA1549 | chr7:138831381-138981318:- | 7 | 12.5 |
TraB domain containing 2B | ENSG00000269113 | TRABD2B | chr1:47760528-47996895:- | 8 | 8.5 |
netrin G1 | ENSG00000162631 | NTNG1 | chr1:107140007-107483458:+ | 7 | 8 |
sphingomyelin phosphodiesterase 1 | ENSG00000166311 | SMPD1 | chr11:6390431-6394998:+ | 7 | 9 |
reticulon 4 receptor like 2 | ENSG00000186907 | RTN4RL2 | chr11:57460549-57477534:+ | 7 | 7.5 |
reticulon 4 receptor like 1 | ENSG00000185924 | RTN4RL1 | chr17:1934677-2025345:- | 7 | 7 |
neuraminidase 1 | ENSG00000204386 | NEU1 | chr6:31857659-31862906:- | 7 | 9 |
paraoxonase 2 | ENSG00000105854 | PON2 | chr7:95404863-95435329:- | 7 | 13 |
sphingomyelin phosphodiesterase acid like 3B | ENSG00000130768 | SMPDL3B | chr1:27934993-27959157:+ | 7 | 11.5 |
voltage dependent anion channel 1 | ENSG00000213585 | VDAC1 | chr5:133971915-134005133:- | 7 | 16 |
cubilin | ENSG00000107611 | CUBN | chr10:16823964-17129831:- | 8 | 9 |
collagen type XXVI alpha 1 chain | ENSG00000160963 | COL26A1 | chr7:101362820-101559024:+ | 7 | 10 |
enolase 1 | ENSG00000074800 | ENO1 | chr1:8861002-8879249:- | 7 | 14 |
contactin 2 | ENSG00000184144 | CNTN2 | chr1:205043197-205078499:+ | 8 | 9 |
tetratricopeptide repeat domain 17 | ENSG00000052841 | TTC17 | chr11:43358932-43494933:+ | 7 | 8 |
milk fat globule EGF and factor V/VIII domain containing | ENSG00000140545 | MFGE8 | chr15:88898683-88913411:- | 7 | 12 |
sulfatase 2 | ENSG00000196562 | SULF2 | chr20:47656348-47786616:- | 8 | 8.5 |
signal peptide, CUB domain and EGF like domain containing 1 | ENSG00000159307 | SCUBE1 | chr22:43197283-43343388:- | 7 | 7 |
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