GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
ATP binding cassette subfamily A member 2ENSG00000107331ABCA2chr9:137007227-137028922:-710.5
NADPH oxidase 1ENSG00000007952NOX1chrX:100843324-100874345:-810.5
tetraspanin 2ENSG00000134198TSPAN2chr1:115048011-115089500:-810.5
family with sequence similarity 189 member BENSG00000160767FAM189Bchr1:155247205-155255483:-79.5
transmembrane protein 63AENSG00000196187TMEM63Achr1:225845536-225882369:-811.5
tetraspanin 18ENSG00000157570TSPAN18chr11:44726465-44932421:+811.5
solute carrier family 15 member 3ENSG00000110446SLC15A3chr11:60937083-60952530:-79.5
potassium two pore domain channel subfamily K member 7ENSG00000173338KCNK7chr11:65592855-65595996:-89.5
family with sequence similarity 234 member BENSG00000084444KIAA1467chr12:13044284-13142521:+710.5
nuclear envelope integral membrane protein 1ENSG00000166881NEMP1chr12:57055643-57088063:-89.5
tectonic family member 2ENSG00000168778TCTN2chr12:123671113-123708403:+78
solute carrier family 15 member 4ENSG00000139370SLC15A4chr12:128793191-128823983:-711.5
transmembrane and coiled-coil domains 3ENSG00000150403TMCO3chr13:113490995-113554590:+79.5
LDL receptor related protein 10ENSG00000197324LRP10chr14:22871613-22881580:+79
potassium voltage-gated channel subfamily H member 5ENSG00000140015KCNH5chr14:62699454-63102037:-89.5
potassium two pore domain channel subfamily K member 13ENSG00000152315KCNK13chr14:90061765-90185857:+89.5
tetraspanin 3ENSG00000140391TSPAN3chr15:77041404-77083984:-812.5
transmembrane channel like 7ENSG00000170537TMC7chr16:18983934-19063942:+78.5
potassium voltage-gated channel subfamily H member 6ENSG00000173826KCNH6chr17:63523334-63548977:+89.5
transmembrane protein 104ENSG00000109066TMEM104chr17:74776483-74839779:+710.5

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