GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
leucine rich repeats and immunoglobulin like domains 1ENSG00000144749LRIG1chr3:66378797-66501263:-711.5
GRAM domain containing 1CENSG00000178075GRAMD1Cchr3:113828182-113947174:+78.5
transmembrane protein 108ENSG00000144868TMEM108chr3:133038391-133397792:+78.5
ring finger protein 13ENSG00000082996RNF13chr3:149812708-149962139:+79.5
SLIT and NTRK like family member 3ENSG00000121871SLITRK3chr3:165186720-165197109:-89.5
lysosomal associated membrane protein 3ENSG00000078081LAMP3chr3:183122213-183163839:-79.5
solute carrier family 10 member 6ENSG00000145283SLC10A6chr4:86823468-86849263:-78.5
solute carrier family 39 member 8ENSG00000138821SLC39A8chr4:102251041-102431258:-811.5
solute carrier family 22 member 4ENSG00000197208SLC22A4chr5:132294443-132344206:+710.5
notch receptor 4ENSG00000204301NOTCH4chr6:32194843-32224067:-78
PKHD1 ciliary IPT domain containing fibrocystin/polyductinENSG00000170927PKHD1chr6:51615300-52087625:-89
osteoclastogenesis associated transmembrane protein 1ENSG00000081087OSTM1chr6:108041409-108165854:-711.5
discoidin, CUB and LCCL domain containing 1ENSG00000164465DCBLD1chr6:117453817-117569858:+712.5
serine incorporator 1ENSG00000111897SERINC1chr6:122443354-122471822:-712.5
adenylate cyclase 1ENSG00000164742ADCY1chr7:45574140-45723116:+89.5
endosome-lysosome associated apoptosis and autophagy regulator family member 2ENSG00000164659KIAA1324Lchr7:86876906-87059699:-710.5
potassium voltage-gated channel subfamily D member 2ENSG00000184408KCND2chr7:120273668-120750331:+89.5
ATPase H+ transporting V0 subunit a4ENSG00000105929ATP6V0A4chr7:138706295-138799560:-810.5
protein tyrosine phosphatase receptor type N2ENSG00000155093PTPRN2chr7:157539056-158587788:-78
solute carrier family 24 member 2ENSG00000155886SLC24A2chr9:19507452-19786928:-810.5

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