GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
FAT atypical cadherin 3ENSG00000165323FAT3chr11:92352096-92896470:+79.5
potassium voltage-gated channel subfamily A member 1ENSG00000111262KCNA1chr12:4909905-4931361:+89.5
potassium voltage-gated channel subfamily A member 5ENSG00000130037KCNA5chr12:5043989-5046788:+89.5
lymphotoxin beta receptorENSG00000111321LTBRchr12:6375045-6391571:+811.5
V-set and immunoglobulin domain containing 10ENSG00000176834VSIG10chr12:118063593-118136026:-79.5
dopachrome tautomeraseENSG00000080166DCTchr13:94436808-94479682:-78.5
solute carrier family 10 member 2ENSG00000125255SLC10A2chr13:103043998-103066846:-89.5
solute carrier family 7 member 8ENSG00000092068SLC7A8chr14:23125295-23183674:-78.5
transmembrane 9 superfamily member 1ENSG00000100926TM9SF1chr14:24189143-24195687:-711.5
solute carrier family 38 member 6ENSG00000139974SLC38A6chr14:60981114-61083733:+89.5
phospholipase D family member 4ENSG00000166428PLD4chr14:104924816-104937790:+712
family with sequence similarity 174 member BENSG00000185442FAM174Bchr15:92617443-92809884:-78.5
calcium voltage-gated channel subunit alpha1 HENSG00000196557CACNA1Hchr16:1153241-1221771:+89.5
adenylate cyclase 7ENSG00000121281ADCY7chr16:50246137-50318135:+810.5
transmembrane 4 L six family member 5ENSG00000142484TM4SF5chr17:4771884-4783213:+78.5
potassium inwardly rectifying channel subfamily J member 18ENSG00000260458KCNJ18chr17:21692523-21704612:+78.5
ecotropic viral integration site 2BENSG00000185862EVI2Bchr17:31303766-31314112:-712.5
transmembrane protein 132EENSG00000181291TMEM132Echr17:34580749-34639318:+78.5
gap junction protein delta 3ENSG00000183153GJD3chr17:40362931-40363815:-89.5
ATP binding cassette subfamily C member 3ENSG00000108846ABCC3chr17:50634777-50692252:+79.5

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