GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
gamma-aminobutyric acid type A receptor subunit alpha6ENSG00000145863GABRA6chr5:161547063-161702593:+89.5
gamma-aminobutyric acid type A receptor subunit piENSG00000094755GABRPchr5:170763350-170814047:+89.5
solute carrier family 17 member 1ENSG00000124568SLC17A1chr6:25782897-25832059:-78.5
butyrophilin subfamily 1 member A1ENSG00000124557BTN1A1chr6:26501221-26510422:+89.5
solute carrier family 44 member 4ENSG00000204385SLC44A4chr6:31863192-31879046:-78.5
major histocompatibility complex, class II, DQ alpha 2ENSG00000237541HLA-DQA2chr6:32741342-32747215:+79.5
solute carrier family 22 member 7ENSG00000137204SLC22A7chr6:43295694-43305538:+78.5
solute carrier family 17 member 5ENSG00000119899SLC17A5chr6:73593379-73654155:-712.5
claudin 20ENSG00000171217CLDN20chr6:155264013-155276548:+89.5
solute carrier family 22 member 1ENSG00000175003SLC22A1chr6:160121789-160158718:+78.5
unc-93 homolog AENSG00000112494UNC93Achr6:167271169-167316019:+78.5
zonadhesin (gene/pseudogene)ENSG00000146839ZANchr7:100733626-100797797:+78.5
claudin 15ENSG00000106404CLDN15chr7:101232092-101238820:-89.5
solute carrier family 26 member 4ENSG00000091137SLC26A4chr7:107660635-107717809:+89.5
maltase-glucoamylaseENSG00000257335MGAMchr7:141907813-142106747:+78.5
cholinergic receptor nicotinic beta 3 subunitENSG00000147432CHRNB3chr8:42697376-42737407:+89.5
transmembrane protein 67ENSG00000164953TMEM67chr8:93754844-93819234:+79.5
solute carrier family 52 member 2ENSG00000185803SLC52A2chr8:144354135-144361272:+712.5
solute carrier family 39 member 4ENSG00000147804SLC39A4chr8:144409742-144416895:-810.5
very low density lipoprotein receptorENSG00000147852VLDLRchr9:2621834-2660053:+712.5

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