GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
glycoprotein Ib platelet subunit betaENSG00000203618GP1BBchr22:19722945-19724771:+78.5
solute carrier family 2 member 11ENSG00000133460SLC2A11chr22:23856703-23886309:+79.5
phosphoinositide-3-kinase interacting protein 1ENSG00000100100PIK3IP1chr22:31281593-31292534:-711.5
potassium inwardly rectifying channel subfamily J member 4ENSG00000168135KCNJ4chr22:38426327-38455199:-78.5
ATPase plasma membrane Ca2+ transporting 2ENSG00000157087ATP2B2chr3:10324023-10708031:-810.5
solute carrier family 6 member 1ENSG00000157103SLC6A1chr3:10992724-11039247:+89.5
claudin 11ENSG00000013297CLDN11chr3:170418865-170860380:+810.5
claudin 1ENSG00000163347CLDN1chr3:190305701-190322475:-810.5
claudin 16ENSG00000113946CLDN16chr3:190322541-190412143:+810.5
solute carrier family 51 subunit alphaENSG00000163959SLC51Achr3:196211487-196243178:+89.5
cholinergic receptor nicotinic alpha 9 subunitENSG00000174343CHRNA9chr4:40335329-40355217:+89.5
gamma-aminobutyric acid type A receptor subunit gamma1ENSG00000163285GABRG1chr4:46035769-46124081:-89.5
gamma-aminobutyric acid type A receptor subunit alpha4ENSG00000109158GABRA4chr4:46918900-46994407:-89.5
gamma-aminobutyric acid type A receptor subunit beta1ENSG00000163288GABRB1chr4:46993723-47426444:+89.5
endogenous retrovirus group MER34 member 1, envelopeENSG00000226887ERVMER34-1chr4:52722618-52751640:-78.5
epidermal growth factorENSG00000138798EGFchr4:109912884-110012266:+89.5
glycine receptor betaENSG00000109738GLRBchr4:157076057-157172090:+89.5
solute carrier family 6 member 19ENSG00000174358SLC6A19chr5:1201595-1225117:+89.5
solute carrier organic anion transporter family member 6A1ENSG00000205359SLCO6A1chr5:102371782-102499016:-89.5
glutamate ionotropic receptor AMPA type subunit 1ENSG00000155511GRIA1chr5:153489615-153813869:+89.5

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