GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
cholinergic receptor nicotinic beta 1 subunit | ENSG00000170175 | CHRNB1 | chr17:7445061-7457707:+ | 8 | 9.5 |
ephrin B3 | ENSG00000108947 | EFNB3 | chr17:7705202-7711378:+ | 8 | 9.5 |
potassium inwardly rectifying channel subfamily J member 12 | ENSG00000184185 | KCNJ12 | chr17:21376197-21419872:+ | 7 | 8.5 |
calcium voltage-gated channel auxiliary subunit gamma 4 | ENSG00000075461 | CACNG4 | chr17:66964910-67033398:+ | 8 | 10.5 |
solute carrier family 16 member 5 | ENSG00000170190 | SLC16A5 | chr17:75087727-75106162:+ | 8 | 9.5 |
phospholipid phosphatase 2 | ENSG00000141934 | PPAP2C | chr19:281040-291504:- | 8 | 12 |
TNF superfamily member 14 | ENSG00000125735 | TNFSF14 | chr19:6661253-6670588:- | 7 | 8.5 |
interleukin 12 receptor subunit beta 1 | ENSG00000096996 | IL12RB1 | chr19:18058995-18098944:- | 8 | 10.5 |
lipolysis stimulated lipoprotein receptor | ENSG00000105699 | LSR | chr19:35248330-35267964:+ | 7 | 12.5 |
calcium voltage-gated channel auxiliary subunit gamma 8 | ENSG00000142408 | CACNG8 | chr19:53963040-53990215:+ | 8 | 9.5 |
syndecan 1 | ENSG00000115884 | SDC1 | chr2:20200797-20225433:- | 7 | 10.5 |
transmembrane protein 150A | ENSG00000168890 | TMEM150A | chr2:85598548-85603196:- | 7 | 8.5 |
dipeptidyl peptidase like 10 | ENSG00000175497 | DPP10 | chr2:114442299-115845752:+ | 7 | 8.5 |
solute carrier family 4 member 10 | ENSG00000144290 | SLC4A10 | chr2:161424332-161985282:+ | 7 | 8.5 |
solute carrier family 52 member 3 | ENSG00000101276 | SLC52A3 | chr20:760080-776015:- | 7 | 8.5 |
signal regulatory protein gamma | ENSG00000089012 | SIRPG | chr20:1629152-1657779:- | 8 | 11.5 |
CD93 molecule | ENSG00000125810 | CD93 | chr20:23079349-23086340:- | 7 | 10.5 |
potassium voltage-gated channel modifier subfamily S member 1 | ENSG00000124134 | KCNS1 | chr20:45092310-45101112:- | 8 | 9.5 |
solute carrier family 13 member 3 | ENSG00000158296 | SLC13A3 | chr20:46557823-46684467:- | 7 | 8.5 |
glutamate ionotropic receptor kainate type subunit 1 | ENSG00000171189 | GRIK1 | chr21:29536933-29940033:- | 8 | 9.5 |
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