GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
killer cell lectin like receptor C2ENSG00000205809KLRC2chr12:10426854-10442300:-78.5
transmembrane 7 superfamily member 3ENSG00000064115TM7SF3chr12:26973195-27014434:-79.5
limb development membrane protein 1 likeENSG00000139636LMBR1Lchr12:49096551-49110900:-79.5
major intrinsic protein of lens fiberENSG00000135517MIPchr12:56449502-56469166:-810.5
protein tyrosine phosphatase receptor type QENSG00000139304PTPRQchr12:80402178-80680234:+79
transient receptor potential cation channel subfamily V member 4ENSG00000111199TRPV4chr12:109783085-109833401:-810.5
TNF superfamily member 13bENSG00000102524TNFSF13Bchr13:108251240-108308484:+78
solute carrier family 22 member 17ENSG00000092096SLC22A17chr14:23346306-23352912:-78.5
solute carrier family 8 member A3ENSG00000100678SLC8A3chr14:70044217-70189070:-78.5
delta like non-canonical Notch ligand 1ENSG00000185559DLK1chr14:100725705-100738224:+78.5
gamma-aminobutyric acid type A receptor subunit gamma3ENSG00000182256GABRG3chr15:26971282-27541991:+89.5
gap junction protein delta 2ENSG00000159248GJD2chr15:34751032-34754965:-89.5
dual oxidase 2ENSG00000140279DUOX2chr15:45092650-45114344:-89.5
solute carrier family 28 member 1ENSG00000156222SLC28A1chr15:84884654-84945796:+89.5
sodium channel epithelial 1 subunit betaENSG00000168447SCNN1Bchr16:23278231-23381299:+78.5
serine protease 8ENSG00000052344PRSS8chr16:31131433-31135762:-78
ATP binding cassette subfamily C member 11ENSG00000121270ABCC11chr16:48166910-48247568:-89.5
solute carrier family 12 member 3ENSG00000070915SLC12A3chr16:56865207-56915850:+89.5
potassium voltage-gated channel modifier subfamily G member 4ENSG00000168418KCNG4chr16:84218667-84239750:-89.5
cholinergic receptor nicotinic epsilon subunitENSG00000108556CHRNEchr17:4897774-4903074:-89.5

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