GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
immunoglobulin superfamily member 3ENSG00000143061IGSF3chr1:116574399-116667755:-713
atypical chemokine receptor 1 (Duffy blood group)ENSG00000213088ACKR1chr1:159203307-159206500:+79
ATPase Na+/K+ transporting subunit alpha 2ENSG00000018625ATP1A2chr1:160115759-160143591:+710.5
ATPase Na+/K+ transporting subunit alpha 4ENSG00000132681ATP1A4chr1:160151570-160186977:+711.5
glycoprotein A33ENSG00000143167GPA33chr1:167052836-167166479:-710.5
ATPase plasma membrane Ca2+ transporting 4ENSG00000058668ATP2B4chr1:203626561-203744081:+816.5
lymphocyte transmembrane adaptor 1ENSG00000122188LAX1chr1:203765176-203776233:+78.5
solute carrier family 41 member 1ENSG00000133065SLC41A1chr1:205789093-205813748:-810.5
gap junction protein gamma 2ENSG00000198835GJC2chr1:228149852-228159826:+89.5
BMP and activin membrane bound inhibitorENSG00000095739BAMBIchr10:28677342-28682939:+78.5
lymphatic vessel endothelial hyaluronan receptor 1ENSG00000133800LYVE1chr11:10556966-10611689:-89.5
transmembrane protein 132AENSG00000006118TMEM132Achr11:60924463-60937159:+813
diacylglycerol lipase alphaENSG00000134780DAGLAchr11:61680433-61747001:+810.5
solute carrier family 22 member 8ENSG00000149452SLC22A8chr11:62989154-63015839:-78.5
solute carrier family 22 member 12ENSG00000197891SLC22A12chr11:64590641-64602353:+78.5
N-acetylated alpha-linked acidic dipeptidase like 1ENSG00000168060NAALADL1chr11:65044818-65058549:-78
anoctamin 1ENSG00000131620ANO1chr11:70078302-70189528:+78.5
glutamate ionotropic receptor AMPA type subunit 4ENSG00000152578GRIA4chr11:105609994-105982092:+89.5
5-hydroxytryptamine receptor 3AENSG00000166736HTR3Achr11:113974881-113990313:+89.5
glutamate ionotropic receptor kainate type subunit 4ENSG00000149403GRIK4chr11:120511759-120988904:+89.5

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