GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
KIAA0319ENSG00000137261KIAA0319chr6:24544104-24646155:-89.5
butyrophilin subfamily 3 member A2ENSG00000186470BTN3A2chr6:26365159-26378320:+811.5
major histocompatibility complex, class I, GENSG00000204632HLA-Gchr6:29826967-29831125:+813.5
major histocompatibility complex, class II, DQ beta 2ENSG00000232629HLA-DQB2chr6:32756098-32763534:-710
triggering receptor expressed on myeloid cells 2ENSG00000095970TREM2chr6:41158506-41163186:-78.5
glutamate ionotropic receptor kainate type subunit 2ENSG00000164418GRIK2chr6:101398788-102070083:+810.5
delta like canonical Notch ligand 1ENSG00000198719DLL1chr6:170282206-170306565:-78.5
cadherin related family member 3ENSG00000128536CDHR3chr7:105876796-106033773:+89.5
Kell metallo-endopeptidase (Kell blood group)ENSG00000197993KELchr7:142941114-142962681:-78.5
neuregulin 1ENSG00000157168NRG1chr8:31639386-32767959:+79.5
solute carrier organic anion transporter family member 5A1ENSG00000137571SLCO5A1chr8:69667047-69835064:-89.5
interleukin 1 receptor accessory protein like 1ENSG00000169306IL1RAPL1chrX:28587399-29956723:+78.5
G protein-coupled receptor 119ENSG00000147262GPR119chrX:130384440-130385447:-78.5
interleukin 9 receptorENSG00000124334IL9RchrX:155997581-156010817:+78.5
gamma-aminobutyric acid type A receptor subunit deltaENSG00000187730GABRDchr1:2019324-2030751:+89.5
podoplaninENSG00000162493PDPNchr1:13583465-13617957:+79.5
gap junction protein beta 5ENSG00000189280GJB5chr1:34755047-34758512:+89.5
gap junction protein alpha 4ENSG00000187513GJA4chr1:34792998-34795747:+89.5
bestrophin 4ENSG00000142959BEST4chr1:44783585-44787705:-78.5
interleukin 12 receptor subunit beta 2ENSG00000081985IL12RB2chr1:67307364-67396900:+89.5

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