GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
sodium voltage-gated channel alpha subunit 4 | ENSG00000007314 | SCN4A | chr17:63938554-63972918:- | 8 | 10.5 |
desmocollin 1 | ENSG00000134765 | DSC1 | chr18:31129236-31162856:- | 8 | 12.5 |
dynactin associated protein | ENSG00000178690 | DYNAP | chr18:54587757-54599493:+ | 7 | 8.5 |
cadherin 20 | ENSG00000101542 | CDH20 | chr18:61333582-61555773:+ | 7 | 8.5 |
cadherin 7 | ENSG00000081138 | CDH7 | chr18:65750252-65890341:+ | 8 | 9.5 |
CD320 molecule | ENSG00000167775 | CD320 | chr19:8302127-8308356:- | 7 | 12.5 |
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) | ENSG00000105371 | ICAM4 | chr19:10286967-10288522:+ | 8 | 9.5 |
erythropoietin receptor | ENSG00000187266 | EPOR | chr19:11377205-11384342:- | 7 | 8.5 |
bestrophin 2 | ENSG00000039987 | BEST2 | chr19:12751702-12758458:+ | 7 | 9 |
IGF like family receptor 1 | ENSG00000126246 | IGFLR1 | chr19:35738801-35742453:- | 8 | 11.5 |
fms related receptor tyrosine kinase 3 ligand | ENSG00000090554 | FLT3LG | chr19:49474207-49486231:+ | 7 | 8.5 |
leukocyte immunoglobulin like receptor B3 | ENSG00000204577 | LILRB3 | chr19:54216278-54223506:- | 7 | 9.5 |
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 | ENSG00000125498 | KIR2DL1 | chr19:54769811-54784322:+ | 7 | 8.5 |
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 | ENSG00000240403 | KIR3DL2 | chr19:54850443-54867207:+ | 7 | 9.5 |
ATP binding cassette subfamily G member 5 | ENSG00000138075 | ABCG5 | chr2:43812472-43838865:- | 7 | 9.5 |
transforming growth factor alpha | ENSG00000163235 | TGFA | chr2:70447280-70554193:- | 7 | 8.5 |
CD8a molecule | ENSG00000153563 | CD8A | chr2:86784610-86808396:- | 7 | 8.5 |
interleukin 18 receptor accessory protein | ENSG00000115607 | IL18RAP | chr2:102418689-102452565:+ | 7 | 8.5 |
integral membrane protein 2C | ENSG00000135916 | ITM2C | chr2:230864639-230879248:+ | 8 | 11.5 |
lysosomal associated membrane protein family member 5 | ENSG00000125869 | LAMP5 | chr20:9514358-9530524:+ | 7 | 9.5 |
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