GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
sodium voltage-gated channel alpha subunit 4ENSG00000007314SCN4Achr17:63938554-63972918:-810.5
desmocollin 1ENSG00000134765DSC1chr18:31129236-31162856:-812.5
dynactin associated proteinENSG00000178690DYNAPchr18:54587757-54599493:+78.5
cadherin 20ENSG00000101542CDH20chr18:61333582-61555773:+78.5
cadherin 7ENSG00000081138CDH7chr18:65750252-65890341:+89.5
CD320 moleculeENSG00000167775CD320chr19:8302127-8308356:-712.5
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)ENSG00000105371ICAM4chr19:10286967-10288522:+89.5
erythropoietin receptorENSG00000187266EPORchr19:11377205-11384342:-78.5
bestrophin 2ENSG00000039987BEST2chr19:12751702-12758458:+79
IGF like family receptor 1ENSG00000126246IGFLR1chr19:35738801-35742453:-811.5
fms related receptor tyrosine kinase 3 ligandENSG00000090554FLT3LGchr19:49474207-49486231:+78.5
leukocyte immunoglobulin like receptor B3ENSG00000204577LILRB3chr19:54216278-54223506:-79.5
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1ENSG00000125498KIR2DL1chr19:54769811-54784322:+78.5
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2ENSG00000240403KIR3DL2chr19:54850443-54867207:+79.5
ATP binding cassette subfamily G member 5ENSG00000138075ABCG5chr2:43812472-43838865:-79.5
transforming growth factor alphaENSG00000163235TGFAchr2:70447280-70554193:-78.5
CD8a moleculeENSG00000153563CD8Achr2:86784610-86808396:-78.5
interleukin 18 receptor accessory proteinENSG00000115607IL18RAPchr2:102418689-102452565:+78.5
integral membrane protein 2CENSG00000135916ITM2Cchr2:230864639-230879248:+811.5
lysosomal associated membrane protein family member 5ENSG00000125869LAMP5chr20:9514358-9530524:+79.5

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